亚洲糖尿病生活质量（AsianDQOL）问卷的开发与验证
Development and validation of the Asian Diabetes Quality of Life (AsianDQOL) Questionnaire.
作者信息
Goh S G K, Rusli B N, Khalid B A K
机构信息
Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Jalan Lagoon Selatan, Bandar Sunway 46150, Selangor Darul Ehsan, Malaysia.
Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Jalan Lagoon Selatan, Bandar Sunway 46150, Selangor Darul Ehsan, Malaysia.
出版信息
Diabetes Res Clin Pract. 2015 Jun;108(3):489-98. doi: 10.1016/j.diabres.2015.02.009. Epub 2015 Feb 28.
AIM
To construct a type-2 diabetes specific quality of life (QOL) tool for Asian populations that is valid and reliable across different ethnicities, languages, and socio-economic backgrounds.
METHODS
A focus group determined the domains affecting QOL in consultation with an expert group. A pilot study was conducted to validate the Asian Diabetes QOL (AsianDQOL) in English, Malay and Chinese-Mandarin. The World Health Organization Brief Quality of Life Questionnaire (WHOQOL-BREF) was used for comparison. Exploratory factor analysis (EFA), reliability analysis (RA) using Cronbach's alpha, test-retest reliability, and confirmatory factor analysis (CFA) using structural equation modeling (SEM) was undertaken using the statistical software IBM SPSS Statistics version 20.
RESULTS
EFA with eigenvalues (>1) and factor loadings ≥0.3 for English and Malay language demonstrated 21 items (5 components). CFA (English version) confirmed the model (CMIN 201.08, p-value 0.071, GFI 0.88, RMSEA 0.036, CFI 0.978). CFA (Malay version) confirmed the 5-factor model (CMIN 189.39, p-value 0.085, GFI 0.937, RMSEA 0.025, CFI 0.987). The Cronbach's alpha scores (English version) were 0.917, 0.818, 0.816, 0.749 and 0.719, respectively. The Malay version scored 0.833, 0.819, 0.816, 0.775, 0.673, respectively, whilst the Chinese/Mandarin version scored 0.890, 0.719, 0.826, 0.862 and 0.759, respectively. Test-retest reliability showed Pearson correlation of 0.600 (English version), 0.700 (Malay version) and 0.500 (Chinese-Mandarin version). A scoring system was generated based on the 25th, 50th and 75th centiles for all the three languages.
CONCLUSION
The AsianDQOL is a valid, reliable and stable tool for assessing QOL in multi-ethnic and multi-lingual T2DM Asian populations.
目的
构建一种适用于亚洲人群的2型糖尿病特异性生活质量（QOL）工具，该工具在不同种族、语言和社会经济背景下均有效且可靠。
方法
一个焦点小组与专家组协商确定影响生活质量的领域。进行了一项试点研究，以验证英文、马来文和中文普通话版本的亚洲糖尿病生活质量量表（AsianDQOL）。使用世界卫生组织生活质量简表（WHOQOL - BREF）进行比较。使用统计软件IBM SPSS Statistics 20版进行探索性因子分析（EFA）、使用克朗巴哈系数的信度分析（RA）、重测信度以及使用结构方程模型（SEM）的验证性因子分析（CFA）。
结果
英文和马来文版本特征值（>1）和因子载荷≥0.3的探索性因子分析显示有21个条目（5个维度）。验证性因子分析（英文版）证实了该模型（CMIN = 201.08，p值 = 0.071，GFI = 0.88，RMSEA = 0.036，CFI = 0.978）。验证性因子分析（马来文版）证实了5因子模型（CMIN = 189.39，p值 = 0.085，GFI = 0.937，RMSEA = 0.025，CFI = 0.987）。克朗巴哈系数得分（英文版）分别为0.917、0.818、0.816、0.749和0.719。马来文版得分分别为0.833、0.819、0.816、0.775、0.673，而中文普通话版得分分别为0.890、0.719、0.826、0.862和0.759。重测信度显示，英文版的皮尔逊相关系数为0.600，马来文版为0.700，中文普通话版为0.500。基于三种语言的第25、50和75百分位数生成了一个评分系统。
结论
亚洲糖尿病生活质量量表（AsianDQOL）是评估多民族、多语言的亚洲2型糖尿病患者生活质量的有效、可靠且稳定的工具。
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