Iroaganachi Mercy, Eleazu Chinedum, Okafor Polycarp
Department of Food Science and Technology, Abia State Polytechnic. Aba, Nigeria.
JOP. 2015 Mar 20;16(2):167-70. doi: 10.6092/1590-8577/2954.
Although unripe plantain (Musa paradisiaca) and ginger (Zingiber officinale) are used as single plants to manage diabetes mellitus in Nigeria, the possibility of combining them in a typical diabetic diet and the glycemic response elicited as a result of such combination has not been investigated.
To determine the effect of unripe plantain and ginger on serum total proteins, albumin, creatinine and urea levels of streptozotocin induced diabetic rats.
Twenty four male albino rats were used and were divided into 4 groups of 6 rats each. Group 1 (non-diabetic) received standard rat feeds; Group 2 (diabetic) received standard rat feeds; Group 3 received unripe plantain pellets and Group 4 received unripe plantain+ginger pellets.
There were significant increases (P=0.045) of both serum urea and creatinine, but significant decreases (P=0.045) of both serum total protein and albumin levels, in Group 2 rats compared with Group 1. There were significant decreases (P=0.033) of both serum urea and creatinine levels of Group 3 and 4 rats compared with Group 2. In addition, there were significant increases of both serum total protein and albumin levels (P=0.033) in Group 3 rats compared with Group 2, but the comparison of serum total protein and albumin levels between Group 4 and Group 2 did not reach the significant level (P=0.056 and P=0.065 for serum total protein and albumin levels, respectively.
Combination of unripe plantain and ginger at the ratio used in the management of renal dysfunction in diabetics was not very effective compared with unripe plantain alone.
在尼日利亚，未成熟的芭蕉（Musa paradisiaca）和生姜（Zingiber officinale）被单独用作治疗糖尿病的植物，但将它们组合在典型糖尿病饮食中的可能性以及这种组合所引发的血糖反应尚未得到研究。
确定未成熟芭蕉和生姜对链脲佐菌素诱导的糖尿病大鼠血清总蛋白、白蛋白、肌酐和尿素水平的影响。
使用24只雄性白化大鼠，将其分为4组，每组6只。第1组（非糖尿病组）给予标准大鼠饲料；第2组（糖尿病组）给予标准大鼠饲料；第3组给予未成熟芭蕉颗粒；第4组给予未成熟芭蕉+生姜颗粒。
与第1组相比，第2组大鼠的血清尿素和肌酐均显著升高（P=0.045），而血清总蛋白和白蛋白水平均显著降低（P=0.045）。与第2组相比，第3组和第4组大鼠的血清尿素和肌酐水平均显著降低（P=0.033）。此外，与第2组相比，第3组大鼠的血清总蛋白和白蛋白水平均显著升高（P=0.033），但第4组与第2组之间血清总蛋白和白蛋白水平的比较未达到显著水平（血清总蛋白和白蛋白水平分别为P=0.056和P=0.065）。
与单独使用未成熟芭蕉相比，按照用于治疗糖尿病患者肾功能不全的比例组合未成熟芭蕉和生姜的效果不是很理想。
