Matsinkou Soh Rosane, Ngaha Damndja Wilfred, Njintang Yanou Nicolas
Department of Food Science and Nutrition, National School of Agro-Industrial Sciences University of Ngaoundere Ngaoundere Cameroon.
Faculty of Sciences University of Ngaoundere Ngaoundere Cameroon.
Food Sci Nutr. 2023 Oct 16;12(1):24-34. doi: 10.1002/fsn3.3764. eCollection 2024 Jan.
Throughout the world, the prevalence of metabolic diseases in general and type 2 diabetes (T2DM) in particular is constantly growing, and sub-Saharan Africa (SSA) is not spared. The use of functional foods is a more practical option among the different approaches used in the management of T2DM owing to the fact that they are relatively less costly, safer, and more accessible. In addition to their low glycemic index just like foods currently used to manage diabetes, functional foods contain bioactive compounds such as polyphenols, dietary fibers, saponins, and peptides. They are so named because they have additional health advantages beyond their basic nutritional worth. Bioactive compounds can be found in a variety of SSA plant-based foods, such as spices, fruits, vegetables, legumes, starchy foods, prepared foods, mixed foods, and prepared dishes. The goal of this review is to highlight some of the investigations into the effectiveness of local food and their antidiabetic mechanisms that have been studied in various SSA regions. Using the literature review as a basis, the authors state that SSA foods are rich in various bioactive compounds capable of regulating blood sugar through enhanced glucose tolerance, antioxidant effects, insulin sensitivity, and inhibition or activation of some key enzymes of the glucose metabolism that are linked to the prevention and management of T2DM. Many of the cited findings are preliminary, obtained from cell and preclinical studies, and therefore other studies need to be done to demonstrate the full potential of these foods to serve as bases for dietary guidelines.
在全球范围内,一般代谢性疾病尤其是2型糖尿病(T2DM)的患病率持续上升,撒哈拉以南非洲地区(SSA)也未能幸免。在用于管理T2DM的不同方法中,使用功能性食品是一种更实际的选择,因为它们成本相对较低、更安全且更容易获得。除了像目前用于管理糖尿病的食物一样具有低血糖指数外,功能性食品还含有生物活性化合物,如多酚、膳食纤维、皂苷和肽。它们之所以被这样命名,是因为除了基本的营养价值外,它们还有额外的健康益处。生物活性化合物可以在各种SSA地区的植物性食物中找到,如香料、水果、蔬菜、豆类、淀粉类食物、预制食品、混合食品和菜肴。这篇综述的目的是强调一些在SSA不同地区进行的关于当地食物有效性及其抗糖尿病机制的研究。基于文献综述,作者指出SSA地区的食物富含各种生物活性化合物,这些化合物能够通过增强葡萄糖耐量、抗氧化作用以及胰岛素敏感性,以及抑制或激活与T2DM预防和管理相关的一些关键葡萄糖代谢酶来调节血糖。许多引用的研究结果是初步的,来自细胞和临床前研究,因此需要进行其他研究来证明这些食物作为饮食指南基础的全部潜力。