Register Karen B, Ivanov Yury V, Harvill Eric T, Brinkac Lauren, Kim Maria, Losada Liliana
National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa, USA.
Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA.
Genome Announc. 2015 Mar 19;3(2):e00081-15. doi: 10.1128/genomeA.00081-15.
Bordetella hinzii is a Gram-negative bacterium known to infect poultry, humans, rabbits, and rodents. It is an opportunistic pathogen in immunocompromised humans, and some strains cause mild to moderate respiratory disease in turkeys. Little is known as to the degree of genetic diversity within the species or the genetic basis for virulence. Here, we report the genome sequences of six isolates of B. hinzii acquired from humans, rabbits, or turkeys. These data provide a framework for refining the population structure of the genus, establishing relationships among genetically distinct isolates, and developing an understanding of the possible virulence mechanisms of the bacterium.
欣氏博德特氏菌是一种革兰氏阴性细菌，已知可感染家禽、人类、兔子和啮齿动物。它是免疫功能低下人群中的一种机会致病菌，一些菌株会在火鸡中引起轻度至中度呼吸道疾病。关于该物种内的遗传多样性程度或毒力的遗传基础知之甚少。在此，我们报告了从人类、兔子或火鸡中分离出的6株欣氏博德特氏菌的基因组序列。这些数据为完善该属的种群结构、建立基因不同的分离株之间的关系以及了解该细菌可能的毒力机制提供了一个框架。
