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关于百里香(Thymus daenensis Celak.)的批判性综述:植物化学与药理学研究。

A critical overview on Thymus daenensis Celak.: phytochemical and pharmacological investigations.

作者信息

Zarshenas Mohammad M, Krenn Liselotte

机构信息

Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran; E-mail:

Department of Pharmacognosy, University of Vienna, Vienna, Austria.

出版信息

J Integr Med. 2015 Mar;13(2):91-8. doi: 10.1016/S2095-4964(15)60166-2.

DOI:10.1016/S2095-4964(15)60166-2
PMID:25797639
Abstract

Thymus daenensis Celak. is an herb endemic to Iran belonging to the Lamiaceae family. Growing in many parts of Iran, the plant is extensively used in folk medicine. This review was performed to compile phytochemical and pharmacological data of T. daenensis. Databases such as PubMed, Scopus, Web of Science, ScienceDirect, Scientific Information Database, Embase, IranMedex and Google Scholar were searched for the terms "Thymus daenensis" and "Avishan-e-denaii" up to 1st January 2014. Following reported ethnopharmacological uses, various T. daenensis preparations have been investigated for antimicrobial, antioxidant, insecticidal and immunomodulatory effects in recent studies. Moreover, numerous studies have been published on the composition of the herb's essential oil, focusing either on environmental parameters or preparation methods. Due to its high concentration of thymol, the plant's essential oil possesses high antimicrobial activities on human pathogenic strains. However, comprehensive studies on the toxicity and teratogenicity as well as clinical efficacy of Thymus daenensis are missing.

摘要

伊朗百里香是一种伊朗特有的草本植物,属于唇形科。这种植物生长在伊朗的许多地区,在民间医学中被广泛使用。本综述旨在汇编伊朗百里香的植物化学和药理学数据。截至2014年1月1日,在PubMed、Scopus、科学网、ScienceDirect、科学信息数据库、Embase、伊朗医学数据库和谷歌学术等数据库中搜索了“伊朗百里香”和“阿维山-德奈伊”等术语。根据已报道的民族药理学用途,近期研究对伊朗百里香的各种制剂进行了抗菌、抗氧化、杀虫和免疫调节作用的研究。此外,关于该草药精油成分的大量研究已经发表,这些研究要么侧重于环境参数,要么侧重于制备方法。由于其百里香酚浓度高,该植物的精油对人类致病菌株具有很高的抗菌活性。然而,目前尚缺乏关于伊朗百里香的毒性、致畸性以及临床疗效的综合研究。

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