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肾皮质厚度作为慢性肾病患者肾功能损害预测指标的价值。

Value of renal cortical thickness as a predictor of renal function impairment in chronic renal disease patients.

作者信息

Yamashita Samia Rafael, von Atzingen Augusto Castelli, Iared Wagner, Bezerra Alexandre Sérgio de Araújo, Ammirati Adriano Luiz, Canziani Maria Eugênia Fernandes, D'Ippolito Giuseppe

机构信息

MD, Radiologist, Collaborator at Unit of Radiology and Imaging Diagnosis, Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

PhD, Radiologist, Collaborator at Department of Imaging Diagnosis, Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Assistant Professor at Universidade do Vale do Sapucaí (Univás), Pouso Alegre, MG, Brazil.

出版信息

Radiol Bras. 2015 Jan-Feb;48(1):12-6. doi: 10.1590/0100-3984.2014.0008.

DOI:10.1590/0100-3984.2014.0008
PMID:25798002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4366023/
Abstract

OBJECTIVE

To determine the presence of linear relationship between renal cortical thickness, bipolar length, and parenchymal thickness in chronic kidney disease patients presenting with different estimated glomerular filtration rates (GFRs) and to assess the reproducibility of these measurements using ultrasonography.

MATERIALS AND METHODS

Ultrasonography was performed in 54 chronic renal failure patients. The scans were performed by two independent and blinded radiologists. The estimated GFR was calculated using the Cockcroft-Gault equation. Interobserver agreement was calculated and a linear correlation coefficient (r) was determined in order to establish the relationship between the different renal measurements and estimated GFR.

RESULTS

The correlation between GFR and measurements of renal cortical thickness, bipolar length, and parenchymal thickness was, respectively, moderate (r = 0.478; p < 0.001), poor (r = 0.380; p = 0.004), and poor (r = 0.277; p = 0.116). The interobserver agreement was considered excellent (0.754) for measurements of cortical thickness and bipolar length (0.833), and satisfactory for parenchymal thickness (0.523).

CONCLUSION

The interobserver reproducibility for renal measurements obtained was good. A moderate correlation was observed between estimated GFR and cortical thickness, but bipolar length and parenchymal thickness were poorly correlated.

摘要

目的

确定不同估算肾小球滤过率(GFR)的慢性肾病患者肾皮质厚度、双极长度和实质厚度之间是否存在线性关系,并使用超声评估这些测量值的可重复性。

材料与方法

对54例慢性肾衰竭患者进行超声检查。扫描由两名独立且不知情的放射科医生进行。使用Cockcroft-Gault方程计算估算的GFR。计算观察者间一致性,并确定线性相关系数(r),以建立不同肾脏测量值与估算GFR之间的关系。

结果

GFR与肾皮质厚度、双极长度和实质厚度测量值之间的相关性分别为中等(r = 0.478;p < 0.001)、较差(r = 0.380;p = 0.004)和较差(r = 0.277;p = 0.116)。皮质厚度和双极长度测量的观察者间一致性被认为是优秀的(0.754),实质厚度测量的观察者间一致性是令人满意的(0.523)。

结论

所获得的肾脏测量值的观察者间可重复性良好。估算GFR与皮质厚度之间观察到中等相关性,但双极长度和实质厚度相关性较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e57/4366023/9726ba06abaa/rb-48-01-0012-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e57/4366023/610e41483d6e/rb-48-01-0012-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e57/4366023/9726ba06abaa/rb-48-01-0012-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e57/4366023/610e41483d6e/rb-48-01-0012-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e57/4366023/9726ba06abaa/rb-48-01-0012-g02.jpg

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