Molajo A O, Bowes R J, Fananapazir L, Slaven Y, Wilkinson K, Blane J, Bennett D H
Pacing Clin Electrophysiol. 1985 Mar;8(2):261-5. doi: 10.1111/j.1540-8159.1985.tb05758.x.
In a randomized prospective study of 150 patients, we compared two porous-tipped, finned leads, one with a vitreous carbon tip (surface area = 12 mm2) and the other with an Elgiloy tip (surface area = 8 mm2). We assessed the acute and chronic stimulation thresholds and the ease of implantation of the two leads. The acute current thresholds for the vitreous carbon and Elgiloy-tipped leads were 1.7 +/- 0.5 (+/- SD) mA vs. 1.1 +/- 0.4 mA (0.25 ms pulse width), 1.3 +/- 0.5 mA vs. 0.9 +/- 0.3 mA (0.5 ms), and 1.0 +/- 0.3 mA vs. 0.8 +/- 0.3 mA (0.75 ms), respectively (P less than 0.0005). Impedance at implantation was 473 +/- 121 ohms and 716 +/- 285 ohms (P less than 0.0005) for the carbon-tipped and Elgiloy-tipped leads, respectively. The R-wave amplitudes were 10.2 +/- 5.1 volts and 6.8 +/- 3.0 volts, respectively (P less than 0.0005). Both leads were easy to implant and showed low stable chronic thresholds from 3 weeks after implantation, at which time the stimulation threshold was 1.9 +/- 1.0 volts vs. 1.5 +/- 0.6 volts with the implanted voltage-variable generators and 1.8 +/- 0.8 mA vs. 1.6 +/- 0.6 mA with the implanted current-variable generators. Reoperation for displacement was required for two of the 87 (2.3%) carbon-tipped and 2 of the 67 (3.2%) Elgiloy-tipped leads. There was no exit block nor any other lead-related complication. We conclude that both leads have similar and satisfactory performance.
在一项针对150例患者的随机前瞻性研究中，我们比较了两种多孔尖端、带鳍的导线，一种导线的尖端为玻璃碳材质（表面积 = 12平方毫米），另一种导线的尖端为埃尔吉洛伊耐蚀合金材质（表面积 = 8平方毫米）。我们评估了这两种导线的急性和慢性刺激阈值以及植入的难易程度。玻璃碳尖端导线和埃尔吉洛伊耐蚀合金尖端导线的急性电流阈值分别为：脉宽0.25毫秒时为1.7±0.5（±标准差）毫安对1.1±0.4毫安，脉宽0.5毫秒时为1.3±0.5毫安对0.9±0.3毫安，脉宽0.75毫秒时为1.0±0.3毫安对0.8±0.3毫安（P＜0.0005）。植入时，碳尖端导线和埃尔吉洛伊耐蚀合金尖端导线的阻抗分别为473±121欧姆和716±285欧姆（P＜0.0005）。R波振幅分别为10.2±5.1伏和6.8±3.0伏（P＜0.0005）。两种导线都易于植入，且自植入后3周起显示出低且稳定的慢性阈值，此时，使用植入式电压可变发生器时，刺激阈值为1.9±1.0伏对1.5±0.6伏，使用植入式电流可变发生器时，刺激阈值为1.8±0.8毫安对1.6±0.6毫安。87根碳尖端导线中有2根（2.3%）、67根埃尔吉洛伊耐蚀合金尖端导线中有2根（3.2%）因导线移位需要再次手术。未出现出口阻滞或任何其他与导线相关的并发症。我们得出结论，两种导线具有相似且令人满意的性能。
