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1550nm铒玻璃飞梭激光与射频微针设备治疗面部萎缩性痤疮瘢痕的疗效及安全性对比研究

Comparative study on efficacy and safety of 1550 nm Er:Glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar.

作者信息

Chae Woong Suk, Seong Jun Young, Jung Ha Na, Kong Sook Hyun, Kim Min Ho, Suh Ho Seok, Choi Yu Sung

机构信息

Department of Dermatology, Ulsan University Hospital, Ulsan, Korea.

Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea.

出版信息

J Cosmet Dermatol. 2015 Jun;14(2):100-6. doi: 10.1111/jocd.12139. Epub 2015 Mar 23.

Abstract

BACKGROUND

The 1550 nm Er:Glass fractional laser is widely used for the treatment of atrophic acne scar. A novel fractional radiofrequency microneedle device has recently emerged as an alternative for treating acne scars.

OBJECTIVES

To evaluate the clinical efficacy and safety of a Er:Glass fractional laser and fractional radiofrequency microneedle device in the treatment of facial atrophic acne scars and to assess the difference between the treatment modalities depending on facial compartment.

METHODS

A total of 40 patients were equally randomized into two groups. Each group of 20 patients received three treatments at 4-week interval using Er:Glass fractional laser or fractional radiofrequency microneedle device.

RESULTS

Scar severity scores (ECCA grading scale) improved by a mean of 25.0% and 18.6% in groups A and B, respectively (both P < 0.01). The difference in the degree of improvement was not statistically significant between the groups after three sessions of treatment. There were no significant side effects.

CONCLUSION

Atrophic acne scars improved in both groups without significant side effects. Additionally, the fractional laser was a more effective treatment option for acne scars, but the fractional radiofrequency microneedle device offered good adherence and short downtime.

摘要

背景

1550纳米铒玻璃点阵激光广泛用于治疗萎缩性痤疮瘢痕。一种新型的射频微针设备最近已成为治疗痤疮瘢痕的替代方法。

目的

评估铒玻璃点阵激光和射频微针设备治疗面部萎缩性痤疮瘢痕的临床疗效和安全性,并根据面部区域评估治疗方式之间的差异。

方法

总共40例患者被平均随机分为两组。每组20例患者使用铒玻璃点阵激光或射频微针设备,每隔4周接受3次治疗。

结果

A组和B组的瘢痕严重程度评分(ECCA分级量表)分别平均改善了25.0%和18.6%(均P<0.01)。经过三次治疗后,两组之间改善程度的差异无统计学意义。没有明显的副作用。

结论

两组的萎缩性痤疮瘢痕均有改善,且无明显副作用。此外,点阵激光是治疗痤疮瘢痕更有效的选择,但射频微针设备具有良好的依从性和较短的停工期。

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