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1550纳米非剥脱性激光治疗中国患者痤疮瘢痕的疗效和安全性:一项半脸对照研究。

Efficacy and safety of 1550-nm fractional laser in the treatment of acne scars in Chinese patients: A split-face comparative study.

作者信息

Yang Qianli, Huang Wen, Qian Hui, Chen Suizhu, Ma Li, Lu Zhong

机构信息

a Department of Dermatology , Huashan Hospital, Fudan University, Shanghai , China.

出版信息

J Cosmet Laser Ther. 2016 Oct;18(6):312-6. doi: 10.1080/14764172.2016.1188211. Epub 2016 Jul 18.

Abstract

OBJECTIVE

To evaluate the efficacy and side effects of 1550-nm fractional Er:Glass laser in treating atrophic acne scar.

MATERIALS AND METHODS

Thirty Chinese patients aged 18-65 with atrophic acne scars on both cheeks received a split-face treatment, one side with four sessions of treatment with fractional 1550-nm Er:Glass laser at 20-day interval and the other with topical asiaticoside cream application three times daily as control. Clinical response and side effects were evaluated by a dermatologist three weeks after each treatment and again 12 weeks after the last laser treatment. In addition, self-evaluation of satisfaction by the patients was done at the end of treatment.

RESULTS

The study found that mean scores decrease after treatment was 5.65 ± 4.34 for the treated side and 1.23 ± 3.41 for the control side. The improvement in acne scars after the fractional Er:Glass laser 1550-nm treatment was more significant than the control side (p = 0.0001). The side effects were mainly local skin irritation and erythema, which disappeared within one week.

CONCLUSION

The research results show that the fractional 1550-nm Er:Glass laser is an effective and safe treatment device for atrophic acne scars.

摘要

目的

评估1550纳米铒玻璃飞梭激光治疗萎缩性痤疮瘢痕的疗效及副作用。

材料与方法

30例年龄在18至65岁之间、双侧脸颊有萎缩性痤疮瘢痕的中国患者接受了分脸治疗,一侧接受4次1550纳米铒玻璃飞梭激光治疗,每次间隔20天,另一侧作为对照,每天外用积雪草苷霜3次。每次治疗后3周及最后一次激光治疗后12周,由皮肤科医生评估临床反应及副作用。此外,在治疗结束时由患者进行满意度自评。

结果

研究发现,治疗侧治疗后平均评分下降5.65±4.34,对照侧为1.23±3.41。1550纳米铒玻璃飞梭激光治疗后痤疮瘢痕的改善程度比对照侧更显著(p = 0.0001)。副作用主要为局部皮肤刺激和红斑,1周内消失。

结论

研究结果表明,1550纳米铒玻璃飞梭激光是治疗萎缩性痤疮瘢痕的一种有效且安全的治疗设备。

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