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富血小板纤维蛋白膜辅助或不辅助冠向复位瓣治疗单纯性牙龈退缩的临床对比评估

Comparative clinical evaluation of coronally advanced flap with or without platelet rich fibrin membrane in the treatment of isolated gingival recession.

作者信息

Thamaraiselvan Murugan, Elavarasu Sugumari, Thangakumaran Suthanthiran, Gadagi Jayaprakash Sharanabasappa, Arthie Thangavelu

机构信息

Department of Periodontics, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India ; Department of Periodontics, J K K Nattaraja Dental College, Komarapalayam, Karnataka, India.

Department of Periodontics, J K K Nattaraja Dental College, Komarapalayam, Karnataka, India.

出版信息

J Indian Soc Periodontol. 2015 Jan-Feb;19(1):66-71. doi: 10.4103/0972-124X.145790.

DOI:10.4103/0972-124X.145790
PMID:25810596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4365161/
Abstract

AIM

The aim of this study was to determine whether the addition of an autologous platelet rich fibrin (PRF) membrane to a coronally advanced flap (CAF) would improve the clinical outcome in terms of root coverage, in the treatment of isolated gingival recession.

MATERIALS AND METHODS

Systemically healthy 20 subjects each with single Miller's class I or II buccal recession defect were randomly assigned to control (CAF) or test (CAF + PRF) group. Clinical outcome was determined by measuring the following clinical parameters such as recession depth (RD), recession width (RW), probing depth (PD), clinical attachment level (CAL), width of keratinized tissue (WKT), gingival thickness (GTH), plaque index (PI), and gingival index (GI) at baseline, 3(rd), and 6(th) month postsurgery.

RESULTS

The root coverage was 65.00 ± 44.47% in the control group and 74.16 ± 28.98% in the test group at 6(th) month, with no statistically significant difference between them. Similarly, CAL, PD, and WKT between the groups were not statistically significant. Conversely, there was statistically significant increase in GTH in the test group.

CONCLUSION

CAF is a predictable treatment for isolated Miller's class I and II recession defects. The addition of PRF to CAF provided no added advantage in terms of root coverage except for an increase in GTH.

摘要

目的

本研究旨在确定在治疗孤立性牙龈退缩时,在冠向复位瓣(CAF)上添加自体富血小板纤维蛋白(PRF)膜是否会在牙根覆盖方面改善临床效果。

材料与方法

选取20名全身健康、患有单个米勒I类或II类颊侧退缩缺损的受试者,随机分为对照组(CAF)和试验组(CAF + PRF)。通过在基线、术后第3个月和第6个月测量以下临床参数来确定临床效果,这些参数包括退缩深度(RD)、退缩宽度(RW)、探诊深度(PD)、临床附着水平(CAL)、角化组织宽度(WKT)、牙龈厚度(GTH)、菌斑指数(PI)和牙龈指数(GI)。

结果

第6个月时,对照组的牙根覆盖率为65.00±44.47%,试验组为74.16±28.98%,两组之间无统计学显著差异。同样,两组之间的CAL、PD和WKT也无统计学显著差异。相反,试验组的GTH有统计学显著增加。

结论

CAF是治疗孤立性米勒I类和II类退缩缺损的可预测治疗方法。在CAF上添加PRF除了增加GTH外,在牙根覆盖方面没有额外优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/d00ec2fb03e2/JISP-19-66-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/ab2c2745ce58/JISP-19-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/e6f324a66275/JISP-19-66-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/d00ec2fb03e2/JISP-19-66-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/ab2c2745ce58/JISP-19-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/e6f324a66275/JISP-19-66-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1475/4365161/d00ec2fb03e2/JISP-19-66-g003.jpg

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The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study.冠状动脉推进瓣联合富血小板纤维蛋白(PRF)和釉基质衍生物治疗牙龈退缩的比较研究。
Eur J Esthet Dent. 2010 Autumn;5(3):260-73.
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Coronally advanced flap versus connective tissue graft in the treatment of multiple gingival recessions: a split-mouth study with a 5-year follow-up.冠向复位瓣术与结缔组织移植术治疗多个牙龈退缩的疗效比较:一项 5 年随访的分侧对照研究。
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注射用富血小板纤维蛋白(i-PRF)作为非手术牙周袋治疗中局部药物递送新载体的疗效:一项随机对照临床试验。
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Comparative evaluation of coronally advanced flap and semilunar coronally repositioned flap, using platelet-rich fibrin in Miller's Class I recession defects: A randomized clinical trial.在米勒I类牙龈退缩缺损中使用富血小板纤维蛋白对冠向推进瓣和半月形冠向复位瓣进行比较评估:一项随机临床试验。
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A comparative study of the effects of advanced platelet-rich fibrin and resorbable collagen membrane in the treatment of gingival recession: a split-mouth, randomized clinical trial.富血小板纤维蛋白和可吸收胶原膜治疗牙龈退缩的对比研究:一项分侧、随机临床试验。
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Three-dimensional architecture and cell composition of a Choukroun's platelet-rich fibrin clot and membrane.
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Re: "Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study".回复:“单独使用改良冠向推进瓣或联合富血小板纤维蛋白膜治疗相邻多个牙龈退缩的临床评估:一项为期6个月的研究”
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Root coverage with a coronally positioned flap used in combination with enamel matrix derivative: 18-month clinical evaluation.联合使用冠向复位瓣和釉基质衍生物进行牙根覆盖:18个月临床评估
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