Legault Zachary, Bagnall Nicholas, Kimmerly Derek S
School of Health and Human Performance, Division of Kinesiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Int J Sport Nutr Exerc Metab. 2015 Oct;25(5):417-26. doi: 10.1123/ijsnem.2014-0209. Epub 2015 Mar 26.
The study aimed to examine the effects that L-glutamine supplementation has on quadriceps muscle strength and soreness ratings following eccentric exercise. It was hypothesized that glutamine ingestion would quicken the recovery rate of peak force production and decrease muscle soreness ratings over a 72-hr recovery period. Sixteen healthy participants (8♀/8♂; 22 ± 4 years) volunteered in a double-blind, randomized, placebo-controlled crossover study. Supplement conditions consisted of isoenergetic placebo (maltodextrin, 0.6 g·kg-1·day-1) and L-glutamine (0.3 g·kg-1·day-1 + 0.3 g·kg-1·day-1 maltodextrin) ingestion once per day over 72 hr. Knee extensor peak torque at 0°, 30°, and 180° per second and muscle soreness were measured before, immediately following, 24, 48, and 72 hr posteccentric exercise. Eccentric exercise consisted of 8 sets (10 repetitions/set) of unilateral knee extension at 125% maximum concentric force with 2-min rest intervals. L-glutamine resulted in greater relative peak torque at 180°/sec both immediately after (71 ± 8% vs. 66 ± 9%), and 72 hr (91 ± 8% vs. 86 ± 7%) postexercise (all, p < .01). In men, L-glutamine produced greater (p < .01) peak torques at 30°/ sec postexercise. Men also produced greater normalized peak torques at 30°/sec (Nm/kg) in the L-glutamine condition than women (all, p < .05). In the entire sample, L-glutamine resulted in lower soreness ratings at 24 (2.8 ± 1.2 vs. 3.4 ± 1.2), 48 (2.6 ± 1.4 vs. 3.9 ± 1.2), and 72 (1.7 ± 1.2 vs. 2.9 ± 1.3) hr postexercise (p < .01). The L-glutamine supplementation resulted in faster recovery of peak torque and diminished muscle soreness following eccentric exercise. The effect of L-glutamine on muscle force recovery may be greater in men than women.
该研究旨在探讨补充L-谷氨酰胺对离心运动后股四头肌力量和酸痛评分的影响。研究假设，摄入谷氨酰胺可加快峰值力量产生的恢复速度，并在72小时的恢复期内降低肌肉酸痛评分。16名健康参与者（8名女性/8名男性；22±4岁）自愿参与一项双盲、随机、安慰剂对照的交叉研究。补充条件包括等能量安慰剂（麦芽糊精，0.6 g·kg-1·天-1）和L-谷氨酰胺（0.3 g·kg-1·天-1+0.3 g·kg-1·天-1麦芽糊精），在72小时内每天摄入一次。在离心运动前、运动后即刻、运动后24、48和72小时测量膝关节伸展在每秒0°、30°和180°时的峰值扭矩以及肌肉酸痛情况。离心运动包括8组（每组10次重复）单侧膝关节伸展，强度为最大向心力量的125%，每组之间休息2分钟。L-谷氨酰胺在运动后即刻（71±8%对66±9%）和运动后72小时（91±8%对86±7%）时，在每秒180°时产生了更大的相对峰值扭矩（所有情况，p<.01）。在男性中，L-谷氨酰胺在运动后每秒30°时产生了更大的（p<.01）峰值扭矩。在L-谷氨酰胺条件下，男性在每秒30°时产生的标准化峰值扭矩（Nm/kg）也高于女性（所有情况，p<.05）。在整个样本中，L-谷氨酰胺在运动后24小时（2.8±1.2对3.4±1.2）、48小时（2.6±1.4对3.9±1.2）和72小时（1.7±1.2对2.9±1.3）时的酸痛评分更低（p<.01）。补充L-谷氨酰胺可使离心运动后峰值扭矩恢复更快，并减轻肌肉酸痛。L-谷氨酰胺对肌肉力量恢复的影响在男性中可能比女性更大。
