Sarkar Malay, Rajta Puja Negi, Khatana Jasmin
Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Department of Physiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Lung India. 2015 Mar-Apr;32(2):142-51. doi: 10.4103/0970-2113.152626.
Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable lifestyle-related disease with high global prevalence. COPD is associated with significant morbidity and mortality worldwide. Comorbidities are important events in the natural history of the disease and have a negative effect on the morbidity and mortality of COPD patients. Cardiac diseases, lung cancer, osteoporosis, and depression are common comorbidities reported for COPD. Recently, anemia has been recognized as a frequent comorbidity in COPD patients. The prevalence of anemia in patients with COPD varies from 7.5% to 33%. Anemia of chronic disease (ACD) is probably the most common type of anemia associated with COPD. ACD is driven by COPD-mediated systemic inflammation. Anemia in COPD is associated with greater healthcare resource utilization, impaired quality of life, decreased survival, and a greater likelihood of hospitalization. We need large prospective studies to discern the association between anemia and COPD.
慢性阻塞性肺疾病（COPD）是一种常见的、可预防和治疗的、与生活方式相关的疾病，在全球范围内具有较高的患病率。COPD在全球范围内与显著的发病率和死亡率相关。合并症是该疾病自然史中的重要事件，对COPD患者的发病率和死亡率有负面影响。心脏病、肺癌、骨质疏松症和抑郁症是COPD常见的合并症。最近，贫血已被认为是COPD患者中常见的合并症。COPD患者中贫血的患病率在7.5%至33%之间。慢性病贫血（ACD）可能是与COPD相关的最常见的贫血类型。ACD是由COPD介导的全身炎症驱动的。COPD中的贫血与更多的医疗资源利用、生活质量受损、生存率降低以及更高的住院可能性相关。我们需要大型前瞻性研究来确定贫血与COPD之间的关联。
