†Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
‡Process Science, Dow Chemical Company, 1710 Building, Midland, Michigan 48674, United States.
Org Lett. 2015 Apr 17;17(8):1866-9. doi: 10.1021/acs.orglett.5b00538. Epub 2015 Mar 30.
The reaction of acid fluorides with N-heterocyclic carbenes (NHCs) produces anhydrous acyl azolium fluorides. With appropriate selection of acid fluoride and NHC, these salts can be used for the room temperature SNAr fluorination of a variety of aryl chlorides and nitroarenes.
酸氟化物与 N-杂环卡宾（NHCs）反应生成无水酰基唑鎓氟化物。通过适当选择酸氟化物和 NHC，可以将这些盐用于各种芳基氯化物和硝基芳烃的室温 SNAr 氟化反应。
