Della Giustina Auro, Landi Massimo, Bellini Federica, Bosoni Mariangela, Ferrante Giuliana, Onorari Marzia, Travaglini Alessandro, Pingitore Giuseppe, Passalacqua Giovanni, Tripodi Salvatore
Department of Pediatrics, National Healthcare System Fornovo, Parma, Italy.
Department of Pediatrics, National Healthcare System ASL TO1, Turin, Italy.
World Allergy Organ J. 2014 Dec 10;7(1):27. doi: 10.1186/1939-4551-7-27. eCollection 2014.
In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergic diseases. Also, Vitamin D supplementation has been assessed as a beneficial approach for treating allergies in some, but not all studies. We reviewed herein the available and relevant literature concerning the possible links between Vitamin D, its supplementation and allergic diseases. A literature search was made independently by the Authors, identifying articles for a narrative review. As per literature, Vitamin D plays a key role in calcium and phosphate metabolism, and it is essential for bone health in infants, children and adolescents. However, there is presently insufficient evidence to support vitamin D supplementation for prevention or treatment of allergic diseases in infants, children and adolescents, concerning allergic rhinitis, asthma, food allergy and atopic dermatitis.
近年来，科学界对维生素D的兴趣逐渐增加，已经开展了多项研究来剖析其在调节过敏性疾病发展/进程中可能发挥的作用。此外，在一些（但并非所有）研究中，补充维生素D已被评估为治疗过敏的一种有益方法。我们在此回顾了有关维生素D、其补充剂与过敏性疾病之间可能联系的现有相关文献。作者们独立进行了文献检索，以确定用于叙述性综述的文章。根据文献，维生素D在钙和磷代谢中起关键作用，对婴儿、儿童和青少年的骨骼健康至关重要。然而，目前尚无足够证据支持在婴儿、儿童和青少年中补充维生素D以预防或治疗过敏性鼻炎、哮喘、食物过敏和特应性皮炎等过敏性疾病。
