Flanagan Helen E, Smith Isabel M, Vaillancourt Tracy, Duku Eric, Szatmari Peter, Bryson Susan, Fombonne Eric, Mirenda Pat, Roberts Wendy, Volden Joanne, Waddell Charlotte, Zwaigenbaum Lonnie, Bennett Teresa, Elsabbagh Mayada, Georgiades Stelios
IWK Health Centre, 5980 University Avenue, Halifax, NS, B3K 6R8, Canada,
J Autism Dev Disord. 2015 Sep;45(9):2691-703. doi: 10.1007/s10803-015-2433-6.
We examined the stability of cognitive and adaptive behaviour standard scores in children with autism spectrum disorder (ASD) between diagnosis and school entry approximately age 6. IQ increased 18 points in 2-year-olds, 12 points in 3-year-olds, and 9 points in 4-year-olds (N = 281). Adaptive behaviour scores increased 4 points across age groups (N = 289). At school entry, 24 % of children met criteria for intellectual disability (cognitive and adaptive behaviour scores <70). No children with both scores ≥70 at diagnosis later met criteria for intellectual disability. Outcomes were more variable for children with initial delays in both areas (in 57 %, both scores remained <70). Findings are relevant to clinical decision-making, including specification of intellectual disability in young children with ASD.
我们研究了自闭症谱系障碍（ASD）儿童在诊断至约6岁入学期间认知和适应性行为标准分数的稳定性。2岁儿童的智商提高了18分，3岁儿童提高了12分，4岁儿童提高了9分（N = 281）。各年龄组的适应性行为分数提高了4分（N = 289）。入学时，24%的儿童符合智力残疾标准（认知和适应性行为分数<70）。诊断时两项分数均≥70的儿童后来无人符合智力残疾标准。在两个领域最初均有延迟的儿童，其结果的变异性更大（57%的儿童两项分数仍<70）。这些发现与临床决策相关，包括对患有ASD的幼儿智力残疾的明确诊断。
