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蜗内阶变化的蜗周型人工耳蜗电极的电生理检测:一项盲法研究

Electrophysiological Detection of Intracochlear Scalar Changing Perimodiolar Cochlear Implant Electrodes: A Blinded Study.

作者信息

Mittmann Philipp, Todt Ingo, Wesarg Thomas, Arndt Susan, Ernst Arneborg, Hassepass Frederike

机构信息

*Department of Otolaryngology at ukb Berlin, Berlin; and †Department of Otolaryngology, Head and Neck Surgery, University of Freiburg, Freiburg, Germany.

出版信息

Otol Neurotol. 2015 Aug;36(7):1166-71. doi: 10.1097/MAO.0000000000000766.

DOI:10.1097/MAO.0000000000000766
PMID:25839979
Abstract

OBJECTIVE

To investigate whether a previous established neural response telemetry (NRT) ratio corresponds with the scalar position of the CI electrode.

STUDY DESIGN

Retrospective blinded controlled study.

SETTING

Tertiary referral center.

PATIENTS

The electrophysiological data sets of 85 patients with measured intraoperative NRTs were evaluated. All patients were implanted with the same CI system. Using a flat panel tomography system, the position of the electrode array was confirmed radiologically.

INTERVENTIONS

The radiological results were blindly compared with the intraoperatively obtained electrophysiological data (NRT ratio) and statistically evaluated. In a second step, irregularities between the NRT ratios and the radiologically confirmed electrode positions were determined and the entire study material was investigated deeper.

MAIN OUTCOME MEASURES

Correlation of the NRT ratio with the intracochlear position of the CI electrode.

RESULTS

By electrophysiological evaluation only, 69 patients were detected without a scalar change at first. In 16 patients, a scalar change was probable. A significant correlation between the radiological results and the NRT ratios was found. Secondly, additional patient characteristics were identified which influences the electrode's position. Excluding those patients, the selectivity and specificity of the NRT ratio could be increased to a higher level.

CONCLUSION

Evidenced by a blinded group of patients, we are able to show that the electrode array position within the cochlea could be predicted using the NRT ratio.

摘要

目的

研究先前建立的神经反应遥测(NRT)比率是否与人工耳蜗(CI)电极的标量位置相对应。

研究设计

回顾性盲法对照研究。

研究地点

三级转诊中心。

患者

对85例术中测量了NRT的患者的电生理数据集进行评估。所有患者均植入了相同的CI系统。使用平板断层扫描系统,通过放射学方法确定电极阵列的位置。

干预措施

将放射学结果与术中获得的电生理数据(NRT比率)进行盲法比较,并进行统计学评估。第二步,确定NRT比率与放射学确认的电极位置之间的不规则性,并对整个研究材料进行更深入的研究。

主要观察指标

NRT比率与CI电极在耳蜗内位置的相关性。

结果

仅通过电生理评估,最初检测到69例患者无标量变化。16例患者可能存在标量变化。发现放射学结果与NRT比率之间存在显著相关性。其次,确定了影响电极位置的其他患者特征。排除这些患者后,NRT比率的选择性和特异性可提高到更高水平。

结论

在一组盲法患者中得到证实,我们能够证明使用NRT比率可以预测耳蜗内电极阵列的位置。

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