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Sensitive high-performance liquid chromatographic assay for albendazole and its main metabolite albendazole sulphoxide in plasma and cerebrospinal fluid.

作者信息

Hurtado M, Medina M T, Sotelo J, Jung H

机构信息

Laboratory of Neuropsychopharmacology, Instituto Nacional de Neurologia y Neurocirugia, Mexico, D.F.

出版信息

J Chromatogr. 1989 Sep 29;494:403-7. doi: 10.1016/s0378-4347(00)82695-x.

DOI:10.1016/s0378-4347(00)82695-x
PMID:2584340
Abstract
摘要

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Sensitive high-performance liquid chromatographic assay for albendazole and its main metabolite albendazole sulphoxide in plasma and cerebrospinal fluid.血浆和脑脊液中阿苯达唑及其主要代谢物阿苯达唑亚砜的灵敏高效液相色谱测定法。
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Enhancing Giardicidal Activity and Aqueous Solubility through the Development of "RetroABZ", a Regioisomer of Albendazole: In Vitro, In Vivo, and In Silico Studies.通过开发“RetroABZ”（阿苯达唑的区域异构体）提高杀贾第鞭毛虫活性和水溶解度：体外、体内和计算研究。
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Concentrations of albendazole in serum, cerebrospinal fluid and hydatidous brain cyst.阿苯达唑在血清、脑脊液和脑包虫囊肿中的浓度。
Neurosurg Rev. 1993;16(1):35-7. doi: 10.1007/BF00308610.
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Dexamethasone increases plasma levels of albendazole.
J Neurol. 1990 Aug;237(5):279-80. doi: 10.1007/BF00314741.
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Antimicrob Agents Chemother. 1992 Apr;36(4):779-82. doi: 10.1128/AAC.36.4.779.