Bozkurt Ibrahim Halil, Yonguc Tarik, Arslan Burak, Degirmenci Tansu, Gunlusoy Bulent, Aydogdu Ozgu, Koras Omer
Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.
Can Urol Assoc J. 2015 Mar-Apr;9(3-4):E122-5. doi: 10.5489/cuaj.2280.
The management of patients with large impacted upper ureteral stones is difficult; there is no standard treatment. We compared the outcomes of percutaneous nephrolithotomy (PCNL) and ureteroscopic lithotripsy (UL) to treat large (≥1.5 cm), impacted, upper ureteral stones.
In total, 86 patients with large impacted upper ureteral stones were included in this study. Of these patients 41 underwent UL and 45 underwent PCNL. The inclusion criteria were: longest diameter of stone ≥1.5 cm, the localization of stone between the lower border of L4 spine and ureteropelvic junction and impacted stone.
In the UL group, we were unable to reach the stone in 3 patients because of ureteral stricture and edema despite balloon dilation. Of these 3 patients, we were unable to optimally visualize the stone in 2 patients due to bleeding and mucosal injury following balloon dilation. The stricture was too firm and could not be passed in the third patient. Also in the UL group, 15 patients had stones or big fragments which migrated into the renal collecting system. In the PCNL group, 21 patients had concurrent renal stones <1 cm and stones were successfully removed in all patients. No statistically significant difference was found between groups in terms of operation time. Mean hospital stay was significantly shorter in the UL group. Success rates were 82.3% in the UL group and 97.6% in the PCNL group (p = 0.001).
The recent study confirms that PCNL is a safe and effective minimally invasive procedure with acceptable complication rates in the treatment of patients with large, impacted upper ureteral stones.
巨大嵌顿性上段输尿管结石患者的治疗颇具难度,尚无标准治疗方案。我们比较了经皮肾镜取石术(PCNL)和输尿管镜碎石术(UL)治疗巨大(≥1.5 cm)、嵌顿性上段输尿管结石的疗效。
本研究共纳入86例巨大嵌顿性上段输尿管结石患者。其中41例行UL,45例行PCNL。纳入标准为:结石最长径≥1.5 cm,结石位于L4椎体下缘与输尿管肾盂连接处之间且为嵌顿性结石。
在UL组中,3例患者尽管进行了球囊扩张,但因输尿管狭窄和水肿未能触及结石。在这3例患者中,2例因球囊扩张后出血和黏膜损伤无法清晰观察结石。第3例患者狭窄过于严重无法通过。此外,UL组有15例患者的结石或大碎片移入肾集合系统。PCNL组有21例患者同时合并<1 cm的肾结石,所有患者的结石均成功取出。两组手术时间差异无统计学意义。UL组平均住院时间明显更短。UL组成功率为82.3%,PCNL组为97.6%(p = 0.001)。
近期研究证实,PCNL是一种安全有效的微创手术,在治疗巨大嵌顿性上段输尿管结石患者时并发症发生率可接受。