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通过传输技术获得的透明质酸钠水溶液在25℃下的表征。

Characterization at 25 °C of sodium hyaluronate in aqueous solutions obtained by transport techniques.

作者信息

Mráček Aleš, Gřundělová Lenka, Minařík Antonín, Veríssimo Luís M P, Barros Marisa C F, Ribeiro Ana C F

机构信息

Department of Physics and Material Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G.Masaryka 275, Zlín 762 72, Czech Republic.

Centre of Polymer Systems, Tomas Bata University in Zlín, nám. T.G. Masaryka 5555, Zlín 760 01, Czech Republic,.

出版信息

Molecules. 2015 Apr 2;20(4):5812-24. doi: 10.3390/molecules20045812.

Abstract

Mutual diffusion coefficients, D, were determined for aqueous solutions of sodium hyaluronate (NaHy) at 25 °C and concentrations ranging from 0.00 to 1.00 g·dm(-3) using the Taylor dispersion technique. From these experimental data, it was possible to estimate some parameters, such as the hydrodynamic radius Rh, and the diffusion coefficient at infinitesimal concentration, D0, of hyaluronate ion, permitting us to have a better understanding of the structure of these systems of sodium hyaluronate in aqueous solutions. The additional viscosity measurements were done and Huggins constant, kH, and limiting viscosity number, [η], were computed for interaction NaHy/water and NaHy/NaHy determination.

摘要

使用泰勒分散技术测定了25℃下浓度范围为0.00至1.00 g·dm⁻³的透明质酸钠(NaHy)水溶液的互扩散系数D。根据这些实验数据,可以估算一些参数,如流体动力学半径Rh以及透明质酸根离子在无限稀释浓度下的扩散系数D0,这使我们能够更好地理解透明质酸钠在水溶液中的这些体系的结构。还进行了增比粘度测量,并计算了哈金斯常数kH和特性粘度[η],用于确定NaHy/水和NaHy/NaHy之间的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1fb/6272485/a86659bb706b/molecules-20-05812-g001.jpg

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