Abubakar Muhammad, Khan Ehtisham-ul-Haq, Arshed Muhammad Javed, Gonzales Jose, Ferrari Giancarlo, Hussain Manzoor, Ali Qurban
National Veterinary Laboratory, Park Road, Islamabad, Pakistan,
Arch Virol. 2015 Jun;160(6):1561-4. doi: 10.1007/s00705-015-2409-z. Epub 2015 Apr 9.
Foot-and-mouth disease (FMD) is a livestock disease that has serious economic repercussions. Here, we report the laboratory results for samples from suspected outbreaks that were sent for confirmation of FMD in Pakistan. From January 2010 to December 2011, 132 suspected outbreaks were investigated, and samples from 58 out of the 76 outbreaks sent to the National Veterinary Laboratory (NVL) were positive. The highest proportion of positives were of serotype O (65.52 %), followed by serotype A (24.14 %) and serotype Asia-1 (10.35 %), whereas amongst the samples sent to the World Reference Laboratory, Pirbright, UK (WRL), samples from 48 out of 56 outbreaks were confirmed to be FMD positive, with the following serotypes identified: O (56.25 %), Asia-1 (37.50 %) and A (6.25 %). The outbreaks affected cattle, buffalo and mixed (cattle and buffalo) herds at rates of 91, 70 and 76 %, respectively. The trend of positive outbreaks was higher in the months of winter and late spring (November to April). Although the serotype O isolates and some of the serotype A isolates from the field samples resembled the vaccine strains (r-value ≥ 0.3), this was not the case for the Asia-1 isolates. These results help to improve our understanding of the occurrence and distribution of FMD in cattle and buffaloes in Pakistan and to provide baseline information for the FMD progressive control program in the country.
口蹄疫是一种对畜牧业有严重经济影响的疾病。在此，我们报告了从巴基斯坦疑似疫情暴发点采集并送去确认口蹄疫的样本的实验室检测结果。2010年1月至2011年12月，共调查了132起疑似疫情，送往国家兽医实验室（NVL）的76起疫情中的58起样本呈阳性。阳性样本中比例最高的是O型（65.52%），其次是A型（24.14%）和亚洲1型（10.35%）；而送往英国皮尔布赖特世界参考实验室（WRL）的样本中，56起疫情中的48起被确诊为口蹄疫阳性，鉴定出的血清型如下：O型（56.25%）、亚洲1型（37.50%）和A型（6.25%）。疫情分别以91%、70%和76%的比例影响牛群、水牛群以及混合（牛和水牛）群体。冬季和晚春月份（11月至4月）阳性疫情的趋势更高。尽管从现场样本中分离出的O型毒株和一些A型毒株与疫苗株相似（r值≥0.3），但亚洲1型毒株并非如此。这些结果有助于增进我们对巴基斯坦牛和水牛口蹄疫发生情况及分布的了解，并为该国口蹄疫逐步控制计划提供基线信息。
