Suppr超能文献

造血干细胞移植患者神经囊尾蚴病的保守治疗:一例报告及文献复习

Conservative management of neurocysticercosis in a patient with hematopoietic stem cell transplantation: a case report and review.

作者信息

Purvey S, Lu K, Mukkamalla S K, Anandi P, Dumitriu B, Kranick S, Hammoud D A, O'Connell E, Oh A L, Barrett J, Mahanty S, Battiwalla M

机构信息

Hematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.

National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland, USA.

出版信息

Transpl Infect Dis. 2015 Jun;17(3):456-62. doi: 10.1111/tid.12392. Epub 2015 Jun 1.

Abstract

Neurocysticercosis, an infection of the central nervous system with the larval stage of the cestode Taenia solium, is common in developing countries but its occurrence and management in allogeneic hematopoietic stem cell transplantation (HSCT) has not been reported previously, to our knowledge. We report the case of an immigrant female patient who underwent a matched-related allogeneic HSCT for acute lymphoblastic leukemia and was incidentally found to have a solitary viable neurocysticercosis lesion. However, despite severe immunosuppression, the size of the cyst did not increase. More importantly, restoration of the immune system did not induce significant inflammation or seizures. Subsequent follow-up demonstrated complete resolution of the neurocysticercosis lesion. Thus, in the setting of HSCT, an asymptomatic patient with a single neurocysticercosis lesion was successfully managed without the use of anthelmintics, steroids, or anti-epileptics.

摘要

神经囊尾蚴病是由绦虫猪带绦虫的幼虫阶段感染中枢神经系统引起的,在发展中国家很常见,但据我们所知,其在异基因造血干细胞移植(HSCT)中的发生情况和管理此前尚未见报道。我们报告了一例移民女性患者,她因急性淋巴细胞白血病接受了匹配相关的异基因HSCT,偶然发现有一个孤立的存活神经囊尾蚴病病灶。然而,尽管存在严重的免疫抑制,囊肿大小并未增加。更重要的是,免疫系统的恢复并未引发明显的炎症或癫痫发作。随后的随访显示神经囊尾蚴病病灶完全消退。因此,在HSCT的情况下,一名患有单个神经囊尾蚴病病灶的无症状患者在未使用驱虫药、类固醇或抗癫痫药的情况下得到了成功治疗。

相似文献

9
Anthelmintics for people with neurocysticercosis.抗寄生虫药物治疗脑囊虫病患者。
Cochrane Database Syst Rev. 2021 Jun 1;6(6):CD000215. doi: 10.1002/14651858.CD000215.pub5.
10
Pediatric Neurocysticercosis.小儿神经囊尾蚴病。
Indian J Pediatr. 2019 Jan;86(1):76-82. doi: 10.1007/s12098-017-2460-8. Epub 2017 Sep 20.

本文引用的文献

2
Epilepsy, cognition and behavior.癫痫、认知与行为。
Indian J Pediatr. 2014 Oct;81(10):1056-62. doi: 10.1007/s12098-014-1530-4. Epub 2014 Jul 31.
6
Extraparenchymal neurocysticercosis in the United States.美国脑实质外神经囊虫病。
Am J Med Sci. 2012 Jul;344(1):79-82. doi: 10.1097/MAJ.0b013e31823e6565.
7
Cerebrovascular complications of neurocysticercosis.神经囊尾蚴病的脑血管并发症
Neurologist. 2012 Jan;18(1):17-22. doi: 10.1097/NRL.0b013e31823d7a80.
8
Corticosteroid use in neurocysticercosis.皮质类固醇在神经囊尾蚴病中的应用。
Expert Rev Neurother. 2011 Aug;11(8):1175-83. doi: 10.1586/ern.11.86.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验