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Can DTI fiber tracking of the optic radiations predict visual deficit after surgery?视辐射的扩散张量成像纤维束示踪能否预测手术后的视力缺损?
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用于癫痫手术中识别视辐射的纤维束成像方法的优势与局限性

Strengths and limitations of tractography methods to identify the optic radiation for epilepsy surgery.

作者信息

Lilja Ylva, Nilsson Daniel T

机构信息

1 Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ; 2 Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

出版信息

Quant Imaging Med Surg. 2015 Apr;5(2):288-99. doi: 10.3978/j.issn.2223-4292.2015.01.08.

DOI:10.3978/j.issn.2223-4292.2015.01.08
PMID:25853086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4379318/
Abstract

Diffusion tensor imaging (DTI) tractography (TG) can visualize Meyer's loop (ML), providing important information for the epilepsy surgery team, both for preoperative counseling and to reduce the frequency of visual field defects after temporal lobe resection (TLR). This review highlights significant steps in the TG process, specifically the processing of raw data including choice of TG algorithm and the interpretation and validation of results. A lack of standardization of TG of the optic radiation makes study comparisons challenging. We discuss results showing differences between studies and uncertainties large enough to be of clinical relevance and present implications of this technique for temporal lobe epilepsy surgery. Recent studies in temporal lobe epilepsy patients, employing TG intraoperatively, show promising results in reduction of visual field defects, with maintained seizure reduction.

摘要

扩散张量成像(DTI)纤维束成像(TG)能够可视化迈耶袢(ML),为癫痫手术团队提供重要信息,无论是用于术前咨询还是降低颞叶切除术(TLR)后视野缺损的发生率。本综述重点介绍了TG过程中的重要步骤,特别是原始数据的处理,包括TG算法的选择以及结果的解释和验证。对视辐射的TG缺乏标准化使得研究比较具有挑战性。我们讨论了显示研究之间差异以及不确定性大到具有临床相关性的结果,并阐述了该技术对颞叶癫痫手术的影响。最近对颞叶癫痫患者进行的术中使用TG的研究显示,在减少视野缺损方面取得了有前景的结果,同时癫痫发作减少情况得以维持。