Ladeira I, Gomes T, Castro A, Ribeiro C, Guimarães M, Taveira N
Resident in the Pulmonology Department of Centro Hospitalar Vila Nova de Gaia/Espinho, EPE, Portugal.
Resident in the Pulmonology Department of Centro Hospitalar Trás-os-Montes e Alto Douro, EPE, Portugal.
Rev Port Pneumol (2006). 2015 Jan-Feb;21(1):11-5. doi: 10.1016/j.rppnen.2014.02.004. Epub 2015 Jan 17.
Chronic Obstructive Pulmonary Disease (COPD) will be the 5th leading cause of disability (DALYs) and the 4th leading cause of death by 2030. Measuring the real impact of COPD using CAT ("COPD Assessment Test") can complement BODE index, an indicator of mortality.
To assess correlation between CAT and BODE index in COPD patients.
A retrospective study was conducted in a population of patients with COPD in a Respiratory Rehabilitation program. We analyzed demographic variables, variables in respiratory function--6 min walking test (6 MWT), post-BD forced expiratory volume in 1st second (FEV1%); dyspnea by mMRC scale; BODE Index and CAT.
The study included 50 patients--GOLD stage I (7), II (25), III (14) and IV (4), 48 men; mean age 62.6 years (± 9.5), average BMI 25.8 kg/m(2) (± 4.8) and FEV1 57.1% (± 19.6); 6 MWT of 443.3m (± 61.6); 46% patients in classes 2 and 3 of mMRC scale; 84% were class 2 in BODE Index. About 80% reported slight to medium impact in CAT. CAT score and impact were correlated with BODE index score: R=0.475, p<0.01, and R=0.377, p=0.004, and BODE index class: R=0.357, p=0.011, and R=0.326, p=0.021.
As pre-existent data in the literature (exacerbations and benefit of rehabilitation in COPD), the positive correlations found with BODE index reinforce the discriminative validity of CAT as a complement in the evaluation of what the true impact of COPD is on a patient's daily life.
到2030年，慢性阻塞性肺疾病（COPD）将成为导致残疾（伤残调整生命年）的第五大主要原因以及导致死亡的第四大主要原因。使用慢性阻塞性肺疾病评估测试（CAT）来衡量COPD的实际影响可以补充作为死亡率指标的BODE指数。
评估COPD患者中CAT与BODE指数之间的相关性。
对参加呼吸康复计划的COPD患者群体进行了一项回顾性研究。我们分析了人口统计学变量、呼吸功能变量——6分钟步行试验（6MWT）、支气管舒张后第1秒用力呼气量（FEV1%）；采用改良英国医学研究委员会（mMRC）量表评估的呼吸困难；BODE指数和CAT。
该研究纳入了50名患者——慢性阻塞性肺疾病全球倡议（GOLD）I期（7例）、II期（25例）、III期（14例）和IV期（4例），48名男性；平均年龄62.6岁（±9.5），平均体重指数25.8kg/m²（±4.8），FEV1为57.1%（±19.6）；6MWT为443.3m（±61.6）；46%的患者处于mMRC量表2级和3级；84%的患者在BODE指数中为2级。约80%的患者报告CAT有轻度至中度影响。CAT评分和影响与BODE指数评分相关：R = 0.475，p<0.01，以及R = 0.377，p = 0.004，与BODE指数分级相关：R = 0.357，p = 0.011，以及R = 0.326，p = 0.021。
正如文献中的现有数据（COPD的急性加重和康复益处）所示，与BODE指数的正相关性加强了CAT作为评估COPD对患者日常生活真正影响的补充指标的判别效度。
