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[飞龙掌血化学成分的研究]

[Study on chemical constituents of Toddalia asiatica].

作者信息

Liu Zhi-gang, Wang Xiang-yu, Mao Bei-ping, Xie Xiao-ling

出版信息

Zhong Yao Cai. 2014 Sep;37(9):1600-3.

PMID:25857161
Abstract

OBJECTIVE

To investigate the chemical constituents of Toddalia asiatica.

METHODS

The compounds were isolated and pu- rified by column chromatography and their structures were identified on the basis of physicochemical properties and spectral data analysis.

RESULTS

Sixteen compounds were isolated and identified as zanthocadinanine A(1), pimpinellin(2), isopimpinellin(3), phellopterin (4), armottianamide(5), chelerythrine(6), nitidine(7), chlorogenic acid (8), toddalolactone (9), protopine(10), skimmianine(11), dictamine(12), toddalenone(13), beta-sitosterol(14), bergapten(15) and 8-hydroxy-6-methoxycoumarin(16).

CONCLUSION

Compound 1 and 16 are isolated from Toddalia genus for the first time.

摘要

目的

研究飞龙掌血的化学成分。

方法

采用柱色谱法分离纯化化合物,并根据理化性质和光谱数据分析鉴定其结构。

结果

分离鉴定出16个化合物,分别为花椒地那宁A(1)、茴芹内酯(2)、异茴芹内酯(3)、茵芋苷(4)、阿诺酰胺(5)、白屈菜红碱(6)、氯化两面针碱(7)、绿原酸(8)、飞龙掌血内酯(9)、原阿片碱(10)、茵芋碱(11)、白鲜碱(12)、飞龙掌血酮(13)、β-谷甾醇(14)、佛手柑内酯(15)和8-羟基-6-甲氧基香豆素(16)。

结论

化合物1和16首次从飞龙掌血属植物中分离得到。

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