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CogState计算机化成套测试在梅奥诊所衰老研究中的表现。

Performance of the CogState computerized battery in the Mayo Clinic Study on Aging.

作者信息

Mielke Michelle M, Machulda Mary M, Hagen Clinton E, Edwards Kelly K, Roberts Rosebud O, Pankratz V Shane, Knopman David S, Jack Clifford R, Petersen Ronald C

机构信息

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; Department of Neurology, Mayo Clinic, Rochester, MN, USA.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.

出版信息

Alzheimers Dement. 2015 Nov;11(11):1367-76. doi: 10.1016/j.jalz.2015.01.008. Epub 2015 Apr 6.

Abstract

INTRODUCTION

The feasibility and validity of brief computerized cognitive batteries at the population-level are unknown.

METHODS

Nondemented participants (n = 1660, age 50-97 years) in the Mayo Clinic Study on Aging completed the computerized CogState battery and standard neuropsychological battery. The correlation between tests was examined and comparisons between CogState performance on the personal computer (PC) and iPad (n = 331), and in the clinic vs. at home (n = 194), were assessed.

RESULTS

We obtained valid data on greater than 97% of participants on each test. Correlations between the CogState and neuropsychological tests ranged from -0.462 to 0.531. Although absolute differences between the PC and iPad were small and participants preferred the iPad, performance on the PC was faster. Participants performed faster on Detection, One Card Learning, and One Back at home compared with the clinic.

DISCUSSION

The computerized CogState battery, especially the iPad, was feasible, acceptable, and valid in the population.

摘要

引言

简短的计算机化认知测试组合在人群层面的可行性和有效性尚不清楚。

方法

梅奥诊所衰老研究中的非痴呆参与者(n = 1660,年龄50 - 97岁)完成了计算机化CogState测试组合和标准神经心理学测试组合。检查了各测试之间的相关性,并评估了个人电脑(PC)和iPad(n = 331)上CogState测试表现之间以及诊所与家中(n = 194)的CogState测试表现之间的差异。

结果

我们在每项测试中获得了超过97%参与者的有效数据。CogState测试与神经心理学测试之间的相关性在 - 0.462至0.531之间。尽管PC和iPad之间的绝对差异很小,且参与者更喜欢iPad,但在PC上的测试表现更快。与诊所相比,参与者在家中进行检测、单卡学习和单项回溯测试时速度更快。

讨论

计算机化CogState测试组合,尤其是iPad,在人群中是可行的、可接受的且有效的。

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