Suppr超能文献

排泄密度和规范在酒精使用障碍中的作用。

The roles of outlet density and norms in alcohol use disorder.

作者信息

Ahern Jennifer, Balzer Laura, Galea Sandro

机构信息

Division of Epidemiology, School of Public Health, University of California, Berkeley, 101 Haviland Hall, Berkeley, CA 94720-7358, USA.

Division of Biostatistics, School of Public Health, University of California, Berkeley, 101 Haviland Hall, Berkeley, CA 94720-7358, USA.

出版信息

Drug Alcohol Depend. 2015 Jun 1;151:144-50. doi: 10.1016/j.drugalcdep.2015.03.014. Epub 2015 Mar 24.

Abstract

BACKGROUND

Alcohol outlet density and norms shape alcohol consumption. However, due to analytic challenges we do not know: (a) if alcohol outlet density and norms also shape alcohol use disorder, and (b) whether they act in combination to shape disorder.

METHODS

We applied a new targeted minimum loss-based estimator for rare outcomes (rTMLE) to a general population sample from New York City (N = 4000) to examine the separate and combined relations of neighborhood alcohol outlet density and norms around drunkenness with alcohol use disorder. Alcohol use disorder was assessed using the World Mental Health Comprehensive International Diagnostic Interview (WMH-CIDI) alcohol module. Confounders included demographic and socioeconomic characteristics, as well as history of drinking prior to residence in the current neighborhood.

RESULTS

Alcohol use disorder prevalence was 1.78%. We found a marginal risk difference for alcohol outlet density of 0.88% (95% CI 0.00-1.77%), and for norms of 2.05% (95% CI 0.89-3.21%), adjusted for confounders. While each exposure had a substantial relation with alcohol use disorder, there was no evidence of additive interaction between the exposures.

CONCLUSIONS

Results indicate that the neighborhood environment shapes alcohol use disorder. Despite the lack of additive interaction, each exposure had a substantial relation with alcohol use disorder and our findings suggest that alteration of outlet density and norms together would likely be more effective than either one alone. Important next steps include development and testing of multi-component intervention approaches aiming to modify alcohol outlet density and norms toward reducing alcohol use disorder.

摘要

背景

酒精销售点密度和规范影响酒精消费。然而,由于分析上的挑战,我们并不清楚:(a)酒精销售点密度和规范是否也会影响酒精使用障碍;(b)它们是否共同作用影响该障碍。

方法

我们将一种针对罕见结局的基于最小损失的新靶向估计器(rTMLE)应用于纽约市的一个普通人群样本(N = 4000),以研究邻里酒精销售点密度和醉酒规范与酒精使用障碍之间的单独及联合关系。使用世界心理健康综合国际诊断访谈(WMH - CIDI)酒精模块评估酒精使用障碍。混杂因素包括人口统计学和社会经济特征,以及在当前邻里居住之前的饮酒史。

结果

酒精使用障碍患病率为1.78%。在对混杂因素进行调整后,我们发现酒精销售点密度的边际风险差异为0.88%(95%置信区间0.00 - 1.77%),规范的边际风险差异为2.05%(95%置信区间0.89 - 3.21%)。虽然每种暴露因素都与酒精使用障碍有显著关系,但没有证据表明这些暴露因素之间存在相加交互作用。

结论

结果表明邻里环境会影响酒精使用障碍。尽管缺乏相加交互作用,但每种暴露因素都与酒精使用障碍有显著关系,我们的研究结果表明,同时改变销售点密度和规范可能比单独改变其中任何一个更有效。接下来重要的步骤包括开发和测试旨在改变酒精销售点密度和规范以减少酒精使用障碍的多成分干预方法。

相似文献

1
The roles of outlet density and norms in alcohol use disorder.排泄密度和规范在酒精使用障碍中的作用。
Drug Alcohol Depend. 2015 Jun 1;151:144-50. doi: 10.1016/j.drugalcdep.2015.03.014. Epub 2015 Mar 24.
9
"Culture of drinking" and individual problems with alcohol use.“饮酒文化”与个人饮酒问题。
Am J Epidemiol. 2008 May 1;167(9):1041-9. doi: 10.1093/aje/kwn022. Epub 2008 Feb 29.

引用本文的文献

2
Space and Place in Alcohol Research.酒精研究中的空间与场所
Curr Epidemiol Rep. 2019 Dec;6(4):412-422. doi: 10.1007/s40471-019-00215-3. Epub 2019 Sep 13.

本文引用的文献

8
Collective efficacy and major depression in urban neighborhoods.社区集体效能与城市社区中的重度抑郁症。
Am J Epidemiol. 2011 Jun 15;173(12):1453-62. doi: 10.1093/aje/kwr030. Epub 2011 Apr 28.
9
Toward DSM-V: mapping the alcohol use disorder continuum in college students.迈向 DSM-V:描绘大学生酒精使用障碍连续谱。
Drug Alcohol Depend. 2011 Nov 1;118(2-3):202-8. doi: 10.1016/j.drugalcdep.2011.03.021. Epub 2011 Apr 22.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验