Iartchouk Oleg, Kozyavkin Sergei, Karamychev Valeri, Slesarev Alexei
Novartis Institutes for BioMedical Research (NIBR), Cambridge, Massachusetts, USA.
Fidelity Systems, Inc., Gaithersburg, Maryland, USA.
Genome Announc. 2015 Apr 9;3(2):e00166-15. doi: 10.1128/genomeA.00166-15.
A new Lactobacillus acidophilus strain, FSI4, isolated from yogurt, was isolated and sequenced in our laboratory. Our data, although supportive of previous conclusions regarding the remarkable stability of L. acidophilus species, indicate accumulating mutations in commercial L. acidophilus strains that warrant further study of the effect of damaged genes on the competitiveness of these bacteria in gut microbiota.
在我们实验室中,从酸奶中分离出了一种新的嗜酸乳杆菌菌株FSI4,并对其进行了测序。我们的数据虽然支持了先前关于嗜酸乳杆菌物种具有显著稳定性的结论,但也表明商业嗜酸乳杆菌菌株中存在累积突变,这值得进一步研究受损基因对这些细菌在肠道微生物群中竞争力的影响。