正常和营养不良仓鼠肌肉中的蛋白质合成。
Protein synthesis in muscles from normal and dystrophic hamsters.
作者信息
Saleem M, Nicholls D M
出版信息
Biochem J. 1979 Apr 15;180(1):51-8. doi: 10.1042/bj1800051.
Abstract
Homogenates of hindleg muscle were obtained from control and dystrophic male hamsters, 30 and 190 days of age, and were used to prepare the postmicrosomal pH5-supernatant fraction. The activity of this fraction in the incorporation of [14C]phenylalanyl-tRNA into peptides was increased in the dystrophic-muscle preparations. No such increase was found in brain or liver preparations from dystrophic hamsters. The increased capacity for aminoacyl-tRNA binding that was observed in preparations from dystrophic animals is discussed.
摘要
从30日龄和190日龄的对照雄性仓鼠和营养不良雄性仓鼠中获取后肢肌肉匀浆，用于制备微粒体后pH5上清液组分。在营养不良肌肉制剂中，该组分将[14C]苯丙氨酰 - tRNA掺入肽中的活性增加。在营养不良仓鼠的脑或肝制剂中未发现这种增加。讨论了在营养不良动物制剂中观察到的氨酰 - tRNA结合能力增加的情况。
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引用本文的文献
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本文引用的文献
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Biochemistry of dystrophic muscle. 2. Some enzyme changes in dystrophic mouse muscle.营养不良性肌肉的生物化学。2. 营养不良小鼠肌肉中的一些酶变化。
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Laser irradiation induces increased activity of liver elongation factor 1.激光照射可诱导肝脏延伸因子1的活性增加。
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Inhibitors of protein synthesis in rat liver microsome fractions.大鼠肝脏微粒体组分中蛋白质合成的抑制剂。
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Muscle fibre growth in five different muscles in both sexes of mice. II. Dystrophic mice.小鼠两性五种不同肌肉中的肌纤维生长。II. 营养不良小鼠。
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Protein synthesis in the myocardiopathy and muscular dystrophy of the Syrian hamster.
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Hereditary myopathy in the Syrian hamster: studies on pathogenesis.叙利亚仓鼠的遗传性肌病：发病机制研究
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Control of the increased protein synthesis in kidney of nephrotic rats by supernatant factors.上清液因子对肾病大鼠肾脏中蛋白质合成增加的控制
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Mechanical properties of dystrophic mouse muscle.营养不良小鼠肌肉的力学特性。
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