Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
Cell. 2015 Apr 9;161(2):201-4. doi: 10.1016/j.cell.2015.03.037.
Although cancer immunotherapy can lead to durable outcomes, the percentage of patients who respond to this disruptive approach remains modest to date. Encouragingly, nanotechnology can enhance the efficacy of immunostimulatory small molecules and biologics by altering their co-localization, biodistribution, and release kinetics.
尽管癌症免疫疗法可以带来持久的疗效，但迄今为止，对这种突破性方法有反应的患者比例仍然不高。令人鼓舞的是，纳米技术可以通过改变免疫刺激小分子和生物制剂的共定位、生物分布和释放动力学来提高它们的疗效。
