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食管黏膜切除术与食管切除术:晚期巨食管患者手术结果的比较研究

Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.

作者信息

de Oliveira Gustavo Carvalho, da Rocha Rodrigo Lima Bastos, Coelho-Neto João de Souza, Terciotti-Junior Valdir, Lopes Luiz Roberto, Andreollo Nelson Adami

机构信息

Departamento de Cirurgia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.

出版信息

Arq Bras Cir Dig. 2015;28(1):28-31. doi: 10.1590/S0102-67202015000100008.

Abstract

BACKGROUND

The surgical treatment of advanced megaesophagus has no consensus, being esophagectomy the more commonly used method. Since it has high morbimortality--inconvenient for benign disease -, in recent years an alternative has been introduced: the esophageal mucosal resection.

AIM

To compare early and late results of the two techniques evaluating the operative time, length of ICU stay; postoperative hospitalization; total hospitalization; intra- and postoperative complication rates; mortality; and long-term results.

METHODS

Were evaluated retrospectively 40 charts, 23 esophagectomies and 17 mucosectomies. In assessing postoperative results, interviews were conducted by using a specific questionnaire.

RESULTS

Comparing the means of esophagectomy and mucosal resection, respectively, the data were: 1) surgical time--310.2 min and 279.7 min (p > 0.05); 2) length of stay in ICU--5 days and 2.53 days (p <0.05); 3) total time of hospitalization--24.25 days and 20.76 days (p> 0.05); 4) length of hospital stay after surgery--19.05 days and 14.94 days (p> 0.05); 5) presence of intraoperative complications--65% and 18% (p <0.05); 6) the presence of postoperative complications - 65% and 35% (p> 0.05). In the assessment of late postoperative score (range 0-10) esophagectomy (n = 5) obtained 8.8 points and 8.8 points also got mucosal resection (n = 5).

CONCLUSIONS

Esophageal mucosal resection proved to be good alternative for surgical treatment of megaesophagus. It was advantageous in the immediate postoperative period by presenting a lower average time in operation, the total hospitalization, ICU staying and complications rate. In the late postoperative period, the result was excellent and good in both operations.

摘要

背景

晚期巨食管的手术治疗尚无共识,食管切除术是更常用的方法。由于其具有高病死率——对良性疾病而言不方便——近年来引入了一种替代方法:食管黏膜切除术。

目的

比较两种技术的早期和晚期结果,评估手术时间、重症监护病房(ICU)住院时间、术后住院时间、总住院时间、术中及术后并发症发生率、死亡率和长期结果。

方法

回顾性评估40份病历,其中23例行食管切除术,17例行黏膜切除术。在评估术后结果时,使用特定问卷进行访谈。

结果

分别比较食管切除术和黏膜切除术的均值,数据如下:1)手术时间——310.2分钟和279.7分钟(p>0.05);2)ICU住院时间——5天和2.53天(p<0.05);3)总住院时间——24.25天和20.76天(p>0.05);4)术后住院时间——19.05天和14.94天(p>0.05);5)术中并发症发生率——65%和18%(p<0.05);6)术后并发症发生率——65%和35%(p>0.05)。在评估术后晚期评分(范围0 - 10分)时,食管切除术(n = 5)得8.8分,黏膜切除术(n = 5)也得8.8分。

结论

食管黏膜切除术被证明是巨食管手术治疗的良好替代方法。它在术后即刻具有优势,手术平均时间、总住院时间、ICU停留时间和并发症发生率较低。在术后晚期,两种手术的结果均为优和良。

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