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Chromosome aberration test and sister-chromatid exchange assay in murine bone marrow cells after in vivo exposure to D-penicillamine alone or combined with cyclophosphamide.

作者信息

Nair N D, Vogel R

机构信息

Bundesgesundheitsamt, Max von Petterkofer-Institut, Berlin, Germany.

出版信息

Mutat Res. 1989 Dec;227(4):237-40. doi: 10.1016/0165-7992(89)90103-6.

DOI:10.1016/0165-7992(89)90103-6
PMID:2586549
Abstract
摘要

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1
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Increased sister-chromatid exchange frequency in preimplantation mouse embryos after maternal cyclophosphamide treatment before implantation.植入前母体环磷酰胺处理后，植入前小鼠胚胎中姐妹染色单体交换频率增加。
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[Ratio of the frequency of chromosome aberrations and sister chromatid exchanges to the dose of the mutagenic exposure to cyclophosphamide in vivo and in vitro].[体内和体外染色体畸变及姐妹染色单体交换频率与环磷酰胺诱变暴露剂量的比值]
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