Netherlands Institute for Pigment Disorders/Department of Dermatology, Academic Medical Centre, Amsterdam, The Netherlands.
Department of Dermatology, MC Haaglanden, Den Haag, The Netherlands.
J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2145-51. doi: 10.1111/jdv.13161. Epub 2015 Apr 13.
Vitiligo is a common depigmenting skin disorder that can influence a patient's quality of life. Although patient-orientated medicine is an emerging concept, a self-assessment tool to assess the degree of depigmentation in vitiligo is not yet available. Therefore, we developed the SAVASI, a self-assessment tool that uses the same basic principles as the VASI.
To assess the validity, reliability and acceptability of the SAVASI.
To assess the validity of the SAVASI, we compared the scores assessed by the patient with the scores of the VASI assessed by the physician. To assess the intra-rater reliability, the correlation between the baseline SAVASI and the SAVASI after 2 weeks was calculated. To assess the acceptability, patients indicated the time needed to complete the SAVASI and the patient assessed the difficulty of the questionnaire on a five-point scale. The Skindex-29 was used to determine the quality of life. The overestimation of the SAVASI compared to the VASI was calculated by subtracting the VASI scores off from the SAVASI scores.
A high correlation between the VASI and the SAVASI (ICC 0.97, 95% CI: 0.95-0.98) was found in 60 patients. The intra-rater reliability of the SAVASI (ICC 0.75, 95% CI 0.54-0.87) was adequate in 31 patients. Fifty (83%) of the patients completed the questionnaire within 10 min and only five (8%) of the patients considered the SAVASI hard. We found no correlation between overestimation of the SAVASI score and the Skindex-29 score.
The SAVASI is a valid, reliable and acceptable self-assessment tool to measure the degree of depigmentation in vitiligo. With the SAVASI the degree of depigmentation can reliably be assessed by the patient themselves which can be useful in large (epidemiological) studies. Furthermore, this could contribute to the patient's disease insight and therapy loyalty.
白癜风是一种常见的色素减退性皮肤病，会影响患者的生活质量。虽然患者导向医学是一个新兴概念，但目前还没有评估白癜风脱色程度的自我评估工具。因此，我们开发了 SAVASI，这是一种使用与 VASI 相同基本原理的自我评估工具。
评估 SAVASI 的有效性、可靠性和可接受性。
为了评估 SAVASI 的有效性，我们将患者评估的分数与医生评估的 VASI 分数进行了比较。为了评估内部评估者的可靠性，计算了基线 SAVASI 与 2 周后 SAVASI 之间的相关性。为了评估可接受性，患者指出完成 SAVASI 所需的时间，并在五分制上评估患者对问卷的难度。使用 Skindex-29 来确定生活质量。通过从 SAVASI 评分中减去 VASI 评分来计算 SAVASI 评分相对于 VASI 评分的高估。
在 60 名患者中，VASI 与 SAVASI 之间存在高度相关性（ICC 0.97，95%CI：0.95-0.98）。在 31 名患者中，SAVASI 的内部评估者可靠性（ICC 0.75，95%CI 0.54-0.87）是足够的。50（83%）名患者在 10 分钟内完成了问卷，只有 5（8%）名患者认为 SAVASI 很难。我们没有发现 SAVASI 评分的高估与 Skindex-29 评分之间存在相关性。
SAVASI 是一种有效的、可靠的和可接受的自我评估工具，用于测量白癜风的脱色程度。使用 SAVASI，患者可以自己可靠地评估脱色程度，这在大型（流行病学）研究中可能很有用。此外，这可以帮助患者了解疾病并提高治疗的忠诚度。
