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奥地利用于蜱传脑炎监测的狍血清。

Roe deer sera used for TBE surveillance in Austria.

作者信息

Duscher Georg Gerhard, Wetscher Monika, Baumgartner Raphaela, Walder Gernot

机构信息

Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Veterinaerplatz 1, A-1210 Vienna, Austria.

Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Veterinaerplatz 1, A-1210 Vienna, Austria.

出版信息

Ticks Tick Borne Dis. 2015 Jun;6(4):489-93. doi: 10.1016/j.ttbdis.2015.03.018. Epub 2015 Apr 11.

DOI:10.1016/j.ttbdis.2015.03.018
PMID:25869034
Abstract

A large majority of Austrian citizens are aware of tick-borne encephalitis (TBE), consequently reflected by a high vaccination rate of 85%. In return, risk assessment and disease mapping on human cases might be hampered due to high and inhomogeneous vaccination rates and travel habitats of humans. The roe deer was used to obtain a starting point for the integral view on the actual risk of TBE in Austria. The roe deer exhibits several attributes which makes it suitable as an indicator species: the roe deer has a restricted home range and it is known to be a heavy tick carrier. Furthermore it sero-converts after infection with TBE, but no outbreak occurs. Sera from 945 roe deer were obtained from all over Austria and screened with IFAT for the antibodies against TBE. Twenty-two positive samples, 2.4%, and 17 samples at the borderline titre of 1:16 were identified. The majority of the positive samples, 70.6%, were located in known TBE areas based on human cases. Further research is needed to confirm or reject new endemic foci of TBE transmission.

摘要

绝大多数奥地利公民都知晓蜱传脑炎(TBE),这一点从85%的高疫苗接种率中得到了体现。反过来,由于疫苗接种率高且不均衡以及人类的旅行栖息地,人类病例的风险评估和疾病分布图绘制可能会受到阻碍。狍被用来作为对奥地利TBE实际风险进行整体评估的起点。狍具有几个使其适合作为指示物种的特性:狍的活动范围有限,并且已知是蜱虫的大量携带者。此外,它在感染TBE后会发生血清转化,但不会爆发疫情。从奥地利各地采集了945只狍的血清,并用间接荧光抗体试验(IFAT)检测了抗TBE抗体。共鉴定出22份阳性样本(2.4%)以及17份临界滴度为1:16的样本。基于人类病例,大部分阳性样本(70.6%)位于已知的TBE区域。需要进一步研究来确认或排除TBE传播的新的地方性疫源地。

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