胃肠道隐球菌瘤——艾滋病患者的免疫重建炎症综合征还是隐球菌复发？

Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

作者信息

Musubire Abdu K, Meya David B, Lukande Robert, Kambugu Andrew, Bohjanen Paul R, Boulware David R

机构信息

Infectious Disease Institute, College of health Sciences, Makerere University, Kampala, Uganda ; Department of Medicine, School of Medicine, College of Health Sciences, Makerere University and Mulago Hospital, Kampala, Uganda.

Infectious Disease Institute, College of health Sciences, Makerere University, Kampala, Uganda ; Division of Infectious Diseases & International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA ; Department of Medicine, School of Medicine, College of Health Sciences, Makerere University and Mulago Hospital, Kampala, Uganda.

出版信息

Med Mycol Case Rep. 2015 Mar 26;8:40-3. doi: 10.1016/j.mmcr.2015.03.004. eCollection 2015 Jun.

The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma.