Rehman Azizur, Rehman Ali, Ahmad Ijaz
Department of Chemistry, Kohat University of Science & Technology (KUST), Khyber Pakhtunkhwa, Kohat 26000, Pakistan.
Int J Anal Chem. 2015;2015:842468. doi: 10.1155/2015/842468. Epub 2015 Mar 19.
Oxalis corniculata is a common medicinal plant widely used against numerous infectious diseases. The agrochemical potential of methanolic extract, n-hexane, chloroform, ethyl acetate, and n-butanol fractions were assessed to measure the antibacterial, antifungal, and insecticidal activities of the plant. The crude, chloroform, and n-butanol soluble fractions showed excellent activities against Escherichia coli, Shigella dysenteriae, Salmonella typhi, and Bacillus subtilis but have no activity against Staphylococcus aureus. Similarly the crude, n-hexane, and chloroform fractions were also found to have significant activity against fungal strains including Fusarium solani, Aspergillus flexneri, and Aspergillus flavus and have no activity against Aspergillus niger. Chemical pesticides have shown very good results at the beginning, but with the passage of time the need was realized to use the natural plant sources for the safe control of insects. The current study will provide minor contribution towards it. High mortality rate was recorded for the crude extract and chloroform fraction against Tribolium castaneum. The two isolated compounds 5-hydroxy-6,7,8,4'-tetramethoxyflavone (1) and 5,7,4'-trihydroxy-6,8-dimethoxyflavone (2) were evaluated for antibacterial, antifungal, and insecticidal activities. The results showed that compound 2 was more active than compound 1 against the tested bacterial strains and insects.
酢浆草是一种常见的药用植物，广泛用于对抗多种传染病。评估了甲醇提取物、正己烷、氯仿、乙酸乙酯和正丁醇馏分的农用化学潜力，以测定该植物的抗菌、抗真菌和杀虫活性。粗提物、氯仿和正丁醇可溶馏分对大肠杆菌、痢疾志贺氏菌、伤寒沙门氏菌和枯草芽孢杆菌表现出优异的活性，但对金黄色葡萄球菌无活性。同样，粗提物、正己烷和氯仿馏分对包括茄病镰刀菌、弗氏曲霉和黄曲霉在内的真菌菌株也具有显著活性，而对黑曲霉无活性。化学农药一开始显示出很好的效果，但随着时间的推移，人们意识到需要使用天然植物来源来安全控制昆虫。当前的研究将对此做出微小贡献。粗提物和氯仿馏分对赤拟谷盗的死亡率很高。对分离得到的两种化合物5-羟基-6,7,8,4'-四甲氧基黄酮（1）和5,7,4'-三羟基-6,8-二甲氧基黄酮（2）进行了抗菌、抗真菌和杀虫活性评估。结果表明，化合物2对受试细菌菌株和昆虫的活性比化合物1更强。
