Perciavalle Valentina, Alagona Giovanna, De Maria Giulia, Rapisarda Giuseppe, Costanzo Erminio, Perciavalle Vincenzo, Coco Marinella
Department of Sciences of Formation, University of Catania, Catania, Italy.
Neurol Sci. 2015 Sep;36(9):1597-601. doi: 10.1007/s10072-015-2210-5. Epub 2015 Apr 17.
We compared, in 20 subjects, the effects of high blood lactate levels on amplitude and latency of P1, N1, P2 and N2 components of lower limb somatosensory evoked potential (SEP), an useful, noninvasive tool for assessing the transmission of the afferent volley from periphery up to the cortex. SEPs were recorded from CPz located over the somatosensory vertex and referenced to FPz with a clavicle ground. Measurements were carried out before, at the end as well as 10 and 20 min after the conclusion of a maximal exercise carried out on a mechanically braked cycloergometer. After the exercise, P2-N2 amplitudes as well as latency of P1 and N1 components showed small but significant reductions. On the contrary, latency of N2 component exhibited a significant increase after the exercise's conclusion. These results suggest that blood lactate appears to have a protective effect against fatigue, at least at level of primary somatosensory cortex, although at the expense of efficiency of adjacent areas.
我们在20名受试者中比较了高血乳酸水平对下肢体感诱发电位（SEP）的P1、N1、P2和N2成分的波幅和潜伏期的影响。SEP是一种用于评估从外周到皮层的传入冲动传导的有用的非侵入性工具。SEP从位于体感顶点的CPz记录，并以锁骨接地参考至FPz。在机械制动的自行车测力计上进行最大运动之前、结束时以及结束后10分钟和20分钟进行测量。运动后，P2-N2波幅以及P1和N1成分的潜伏期显示出虽小但显著的降低。相反，运动结束后N2成分的潜伏期显著增加。这些结果表明，血乳酸似乎至少在初级体感皮层水平对疲劳具有保护作用，尽管是以相邻区域的效率为代价。
