Coco Marinella, Alagona Giovanna, De Maria Giulia, Rapisarda Giuseppe, Costanzo Erminio, Perciavalle Vincenzo, Perciavalle Valentina
Department of Bio-Medical Sciences, Section of Physiology, University of Catania, Catania, Italy.
Neurol Sci. 2015 Apr;36(4):541-6. doi: 10.1007/s10072-014-2015-y. Epub 2014 Nov 26.
We studied, in healthy adult subjects, the association of high blood lactate levels, induced with an exhaustive exercise (12 subjects) or an intravenous infusion (four subjects) of a lactate solution (3 mg/kg in 1 min), with amplitude and latency of visual-evoked potentials. Amplitude of N75, P100, and N145 components did not show significant changes, whereas latency of P100 was reduced at exercise's end and that of N145 increased 10 min after the conclusion. Therefore, an increase of blood lactate induced by an exhaustive exercise or an intravenous infusion appears to induce an improvement in the conduction time between eye and striate cortex, while it seems to evoke a worsening of intracortical communication between striate and extrastriate areas.
我们在健康成年受试者中进行了研究，观察通过力竭运动（12名受试者）或静脉输注乳酸溶液（4名受试者，1分钟内输注3mg/kg）诱导产生的高血乳酸水平与视觉诱发电位的波幅和潜伏期之间的关联。N75、P100和N145成分的波幅未显示出显著变化，而P100的潜伏期在运动结束时缩短，N145的潜伏期在结束后10分钟增加。因此，力竭运动或静脉输注诱导的血乳酸增加似乎会使眼与纹状皮质之间的传导时间得到改善，而似乎会引起纹状区与纹状外区之间皮质内通讯的恶化。
