Solbrig Marylou V, Perng Guey-Chuen
Department of Pharmacology and Toxicology, School of Pharmacy, University of Kansas, 1251 Wescoe Hall Drive, Malott Hall Rm 5040, Lawrence, KS, 66045, USA,
Curr Neurol Neurosci Rep. 2015 Jun;15(6):29. doi: 10.1007/s11910-015-0550-4.
Dengue, a mosquito-borne flavivirus and fastest growing tropical disease in the world, has experienced an explosion of neurologic case reports and series in recent years. Now dengue is a frequent or leading cause of encephalitis in some endemic regions, is estimated to infect one in six tourists returning from the tropics, and has been proven to have local transmission within the continental USA. High documentation of neurologic disease in recent years reflects increases in overall cases, enhanced clinical awareness and advances in diagnostics. Neurological aspects of dengue virus, along with epidemiology, treatment, and vaccine progress, are presented.
登革热是一种由蚊子传播的黄病毒，是世界上增长最快的热带疾病，近年来神经系统病例报告和系列病例急剧增加。如今，在一些流行地区，登革热是脑炎的常见病因或主要病因，据估计，每六名从热带地区返回的游客中就有一人感染登革热，而且已经证实登革热在美国本土有本地传播。近年来对神经系统疾病的大量记录反映了总体病例的增加、临床意识的提高以及诊断技术的进步。本文介绍了登革热病毒的神经学方面，以及流行病学、治疗方法和疫苗进展情况。
