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富血小板血浆治疗皮下静脉通路装置瘢痕:一项直接对比的患者调查

Platelet-rich plasma in the treatment of subcutaneous venous access device scars: a head-to-head patient survey.

作者信息

Eichler C, Najafpour M, Sauerwald A, Puppe J, Warm M

机构信息

Breast Cancer Center, Municipal Hospital Holweide, 51067 Cologne, Germany ; Department of Gynecology and Obstetrics, Municipal Hospital Holweide, 51067 Cologne, Germany.

Department of Gynecology and Obstetrics, Helios Klinikum, 53721 Siegburg, Germany.

出版信息

Biomed Res Int. 2015;2015:630601. doi: 10.1155/2015/630601. Epub 2015 Mar 24.

DOI:10.1155/2015/630601
PMID:25879032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4387981/
Abstract

INTRODUCTION

Platelet-rich plasma (PRP) is a product widely used in sports medicine, tissue repair, and general surgery. A recent meta-analysis showed this product to be beneficial when introduced into a wound area, be it intra-articular (i.e., joint-injections) or direct introduction onto the wound surface.

METHODS

Between the years of 2012 and 2014 a questionnaire evaluating surgical outcome after port (venous access device) removal was answered by 100 patients in the control group and 20 patients in a PRP group, leading to a total of 120 patients in this single center, retrospective, subjective outcome evaluation.

RESULTS

No statistical difference was shown in postsurgical complication rates, postsurgical pain, decreased mobility, and overall quality of life. A significant difference was shown in overall patient satisfaction and the desire to further improve port area scarring. Results differed significantly in favor of the PRP group. Interestingly, approximately 40.2% of patients are dissatisfied with the surgical outcome after port removal in the control group. This result, though surprising, may be improved to 10% dissatisfaction when a PRP product is used.

CONCLUSION

PRP products such as Arthrex ACP are safe to use and present an additional option in improving surgical outcome.

摘要

引言

富血小板血浆(PRP)是一种广泛应用于运动医学、组织修复和普通外科的产品。最近的一项荟萃分析表明,将该产品引入伤口区域(无论是关节内,即关节注射,还是直接引入伤口表面)是有益的。

方法

在2012年至2014年期间,100名对照组患者和20名PRP组患者回答了一份关于端口(静脉通路装置)移除后手术结果的问卷,在这个单中心、回顾性、主观结果评估中,共有120名患者参与。

结果

术后并发症发生率、术后疼痛、活动能力下降和总体生活质量方面未显示出统计学差异。在总体患者满意度和改善端口区域瘢痕的意愿方面显示出显著差异。结果明显有利于PRP组。有趣的是,对照组中约40.2%的患者对端口移除后的手术结果不满意。这一结果虽然令人惊讶,但使用PRP产品时,不满意率可能会降至10%。

结论

Arthrex ACP等PRP产品使用安全,为改善手术结果提供了额外选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/455b/4387981/32c584f71050/BMRI2015-630601.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/455b/4387981/32c584f71050/BMRI2015-630601.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/455b/4387981/32c584f71050/BMRI2015-630601.001.jpg

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A pilot study on the effectiveness of platelet-rich plasma and debridement for the treatment of nonhealing fistulas in spinal cord-injured patients.一项关于富血小板血浆和清创术治疗脊髓损伤患者不愈合瘘管有效性的初步研究。
Adv Skin Wound Care. 2015 Mar;28(3):123-8. doi: 10.1097/01.ASW.0000459845.95441.1a.
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Restorative oncodermatology: Diagnosis and management of dermatologic sequelae from cancer therapies.
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Comparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft.
在使用分层皮片进行创面覆盖之前,传统机械固定与在创面床使用自体富血小板血浆(PRP)的比较。
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[Platelet-rich plasma for treating acute wounds: a meta-analysis].富血小板血浆治疗急性伤口:一项荟萃分析
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