Goyet Sophie, Touch Socheat, Ir Por, SamAn Sovannchhorvin, Fassier Thomas, Frutos Roger, Tarantola Arnaud, Barennes Hubert
Epidemiology and Public Health Unit, Institut Pasteur, Phnom Penh, Cambodia.
School of Public Health, National Institute of Public Health, Phnom Penh, Cambodia.
Implement Sci. 2015 Mar 11;10:32. doi: 10.1186/s13012-015-0217-1.
Evidence-based public health requires that research provides policymakers with reliable and accessible information reflecting the disease threats. We described the scientific production of research in Cambodia and assessed to what extent it provides appropriate insights and implications for practice to guide health policymakers and managers and knowledge relevant for translation.
We conducted a systematic review of scientific articles published on biomedical research in Cambodia. Regression analysis assessed the trends over time and factors associated with actionable messages in the articles' abstracts.
From 2000 to 2012, 628 articles were published in 237 journals with a significant increase over time (from 0.6/million population to 5.9/million population, slope coefficient 7.6, 95% CI 6.5-8.7, p < 0.001). Most publications on diseases addressed communicable diseases (n = 410, 65.3%). Non-communicable diseases (NCD) were under-addressed (7.7% of all publications) considering their burden (34.5% of the disease burden). Of all articles, 67.8% reported descriptive studies and 4.3% reported studies with a high level of evidence; 27.4% of studies were led by an institution based in Cambodia. Factors associated with an actionable message (n = 73, 26.6%) were maternal health (OR 3.08, 95% CI 1.55-6.13, p = 0.001), the first author's institution being Cambodian (OR 1.78, 95% CI 1.06-2.98, p = 0.02) and a free access to full article (OR 3.07, 95% CI 1.08-8.70, p = 0.03). Of all articles, 87% (n = 546) were accessible in full text from Cambodia.
Scientific publications do not fully match with health priorities. Gaps remain regarding NCD, implementation studies, and health system research. A health research agenda would help align research with health priorities. We recommend 1) that the health authorities create an online repository of research findings with abstracts in the local language; 2) that academics emphasize the importance of research in their university teaching; and 3) that the researcher teams involve local researchers and that they systematically provide a translation of their abstracts upon submission to a journal. We conclude that building the bridge between research and public health requires a willful, comprehensive strategy rather than relying solely only publications.
循证公共卫生要求研究为政策制定者提供反映疾病威胁的可靠且易于获取的信息。我们描述了柬埔寨的科研成果，并评估其在多大程度上为实践提供了适当的见解和启示，以指导卫生政策制定者和管理者，以及与转化相关的知识。
我们对柬埔寨发表的生物医学研究科学文章进行了系统综述。回归分析评估了时间趋势以及与文章摘要中可采取行动信息相关的因素。
2000年至2012年期间，237种期刊发表了628篇文章，且随时间显著增加（从每百万人口0.6篇增至每百万人口5.9篇，斜率系数7.6，95%置信区间6.5 - 8.7，p < 0.001）。大多数关于疾病的出版物涉及传染病（n = 410，65.3%）。考虑到非传染性疾病（NCD）的负担（占疾病负担的34.5%），其在出版物中的占比却很低（占所有出版物的7.7%）。在所有文章中，67.8%报告了描述性研究，4.3%报告了具有高证据水平的研究；27.4%的研究由柬埔寨境内的机构主导。与可采取行动信息相关的因素（n = 73，26.6%）包括孕产妇健康（比值比3.08，95%置信区间1.55 - 6.13，p = 0.001）、第一作者所在机构为柬埔寨机构（比值比1.78，95%置信区间1.06 - 2.98，p = 0.02）以及可免费获取全文（比值比3.07，95%置信区间1.08 - 8.70，p = 0.03）。在所有文章中，87%（n = 546）可从柬埔寨获取全文。
科学出版物与卫生优先事项不完全匹配。在非传染性疾病、实施研究和卫生系统研究方面仍存在差距。卫生研究议程将有助于使研究与卫生优先事项保持一致。我们建议：1）卫生当局创建一个以当地语言提供摘要的研究结果在线知识库；2）学者在大学教学中强调研究的重要性；3）研究团队吸纳当地研究人员参与，并在向期刊投稿时系统地提供摘要的翻译。我们得出结论，搭建研究与公共卫生之间桥梁需要一项有意为之的全面战略，而不是仅仅依赖出版物。
