分析增加机械指数和能量沉积对人体肝脏剪切波速度重建的影响。
Analyzing the Impact of Increasing Mechanical Index and Energy Deposition on Shear Wave Speed Reconstruction in Human Liver.
作者信息
Deng Yufeng, Palmeri Mark L, Rouze Ned C, Rosenzweig Stephen J, Abdelmalek Manal F, Nightingale Kathryn R
机构信息
Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
出版信息
Ultrasound Med Biol. 2015 Jul;41(7):1948-57. doi: 10.1016/j.ultrasmedbio.2015.02.019. Epub 2015 Apr 18.
Shear wave elasticity imaging (SWEI) has found success in liver fibrosis staging. This work evaluates hepatic SWEI measurement success as a function of push pulse energy using two mechanical index (MI) values (1.6 and 2.2) over a range of pulse durations. Shear wave speed (SWS) was measured in the livers of 26 study subjects with known or potential chronic liver diseases. Each measurement consisted of eight SWEI sequences, each with different push energy configurations. The rate of successful SWS estimation was linearly proportional to the push energy. SWEI measurements with higher push energy were successful in patients for whom standard push energy levels failed. The findings also suggest that liver capsule depth could be used prospectively to identify patients who would benefit from elevated output. We conclude that there is clinical benefit to using elevated acoustic output for hepatic SWS measurement in patients with deeper livers.
剪切波弹性成像（SWEI）在肝纤维化分期方面已取得成功。这项研究评估了在一系列脉冲持续时间内，使用两个机械指数（MI）值（1.6和2.2）时，肝脏SWEI测量成功率与推注脉冲能量的关系。在26名已知或潜在患有慢性肝病的研究对象的肝脏中测量了剪切波速度（SWS）。每次测量由八个SWEI序列组成，每个序列具有不同的推注能量配置。成功估计SWS的比率与推注能量呈线性比例关系。对于标准推注能量水平失败的患者，使用更高推注能量的SWEI测量是成功的。研究结果还表明，肝包膜深度可前瞻性地用于识别那些将从提高输出中受益的患者。我们得出结论，对于肝脏较深的患者，使用提高的声学输出进行肝脏SWS测量具有临床益处。
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