Matsuno M, Murakami G, Adachi Y, Adachi Y, Kayahara M, Igarashi T
Arerugi. 1989 Oct;38(10):1142-9.
We collected airborne particle from indoor air by using a high-volume air sampler, and measured mite allergens in the air-filter extract by use of RAST inhibition assay. The results obtained were as follows: 1) The assay revealed the presence of house dust mite allergen in the indoor air varying from 690 to 129000 pg/m3. 2) In apartments, seasonal fluctuations of house dust mite allergen in the indoor air demonstrated a peak in autumn (September and October), and showed a tendency to increase in spring. In our outpatient clinic, the quantity of house dust mite allergen in the indoor air varied from 690 to 5670 pg/m3, while there were few mites on the floor, and showed a tendency to increase in winter. 3) There was a significant correlation between the quantity of house dust mite allergen in the indoor air and the number of mite in house dust (r = 0.535, p less than 0.01). 4) The amount of D.f. allergen in the indoor air was significantly decreased by using air cleaners (p less than 0.005). These results showed that the quantification of house dust mite allergen was useful from the clinical point of view as a parameter of mite pollution indoors, and it was important for asthmatics to live in clean environment, and to decrease the number of mites in house dust.
我们使用大容量空气采样器从室内空气中采集空气颗粒物，并通过放射性变应原吸附抑制试验（RAST抑制试验）测定空气过滤器提取物中的螨虫过敏原。所得结果如下：1）该试验显示室内空气中存在屋尘螨过敏原，含量在690至129000 pg/m³之间。2）在公寓中，室内空气屋尘螨过敏原的季节性波动在秋季（9月和10月）出现峰值，春季有增加趋势。在我们的门诊诊所，室内空气屋尘螨过敏原含量在690至5670 pg/m³之间，而地板上螨虫数量很少，冬季有增加趋势。3）室内空气屋尘螨过敏原含量与屋尘中螨虫数量之间存在显著相关性（r = 0.535，p < 0.01）。4）使用空气净化器后，室内空气中粉尘螨过敏原的量显著降低（p < 0.005）。这些结果表明从临床角度来看，定量测定屋尘螨过敏原作为室内螨虫污染的参数是有用的，对于哮喘患者来说，生活在清洁环境中并减少屋尘中的螨虫数量很重要。
