Ito K, Suko M, Miyamoto T, Kobayashi S, Nakazawa T, Takahashi T, Nishikata H, Nemoto T, Matsubara T
Arerugi. 1989 May;38(5):413-22.
In order to examine the usefulness of mite and insect RAST, RAST was carried out on 79 asthmatic patients using mite, cockroach, mosquito and larval chironomid midge (Chironomus thummi thummi, CTT) allergen discs supplied from Pharmacia AB, and discs of two species of adult chironomid midge (Tokunagayusurika akamusi, TA and Chironomus yoshimatsui, CY in Japan) which were prepared in our laboratories. The results were as follows. 1) The positive rate of RAST in 65 randomly selected asthmatic patients was 62% in the case of mite, 25% for TA, 20% for CY, 14% for cockroach, 11% for CTT, 8% for silk and 6% for mosquito. The positive rates of silk and mosquito RAST were low. However, these RAST seemed to be clinically useful when patients were positive to these RAST. 2) The rate of coincidence between skin test and RAST was 86.5% in the case of mite and 30% in the case of silk. The rate of coincidence between prick test using adult CY and RAST using larval CTT was 46.5%. 3) The positive rate of larval CTT RAST was about half that of adult TA or adult CY. However, larval CTT RAST seemed clinically useful when patients were positive to the RAST, because all the patients who were positive to larval CTT RAST were also positive to both adult TA and CY RAST. 4) A significant correlation was found among the three kind of chironomid midge RAST and also between cockroach RAST and any of the three kinds of chironomid midge RASTs.
为了检验螨和昆虫放射变应原吸附试验（RAST）的实用性，我们使用Pharmacia AB公司提供的螨、蟑螂、蚊子和摇蚊幼虫（Chironomus thummi thummi，CTT）变应原盘，以及我们实验室制备的两种成年摇蚊（日本的Tokunagayusurika akamusi，TA和Chironomus yoshimatsui，CY）变应原盘，对79例哮喘患者进行了RAST检测。结果如下：1）在随机选取的65例哮喘患者中，螨RAST阳性率为62%，TA为25%，CY为20%，蟑螂为14%，CTT为11%，蚕丝为8%，蚊子为6%。蚕丝和蚊子RAST的阳性率较低。然而，当患者这些RAST呈阳性时，这些RAST在临床上似乎是有用的。2）皮肤试验与RAST的符合率，螨为86.5%，蚕丝为30%。使用成年CY进行的点刺试验与使用摇蚊幼虫CTT进行的RAST之间的符合率为46.5%。3）摇蚊幼虫CTT RAST的阳性率约为成年TA或成年CY的一半。然而，当患者摇蚊幼虫CTT RAST呈阳性时，该检测在临床上似乎是有用的，因为所有摇蚊幼虫CTT RAST呈阳性的患者成年TA和CY RAST也均为阳性。4）在三种摇蚊RAST之间以及蟑螂RAST与三种摇蚊RAST中的任何一种之间均发现有显著相关性。
