Lehri B, Seddon A M, Karlyshev A V
School of Life Sciences, SEC Faculty, Kingston University, Kingston upon Thames KT1 2EE, UK.
School of Life Sciences, SEC Faculty, Kingston University, Kingston upon Thames KT1 2EE, UK
FEMS Microbiol Lett. 2015 Jun;362(11). doi: 10.1093/femsle/fnv068. Epub 2015 Apr 23.
In this report we describe a Lactobacillus fermentum 3872 plasmid (pLF3872) not previously found in any other strain of this species. The analysis of the complete sequence of this plasmid revealed the presence of a gene encoding a large collagen-binding protein (CBP), as well as the genes responsible for plasmid maintenance and conjugation. Potential roles of CBP and a chromosomally encoded fibronectin-binding protein (FbpA) in probiotic activity are discussed.
在本报告中，我们描述了一种发酵乳杆菌3872质粒（pLF3872），该质粒在该物种的其他菌株中未曾发现过。对该质粒完整序列的分析揭示了一个编码大型胶原结合蛋白（CBP）的基因的存在，以及负责质粒维持和接合的基因。文中讨论了CBP和染色体编码的纤连蛋白结合蛋白（FbpA）在益生菌活性中的潜在作用。
