用纳米结构羟基磷灰石化合物修复的动物模型下颌骨解剖基质的计算机断层扫描（CT）成像。
Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds.
作者信息
Ciuluvică R, Grădinaru S, Popescu M, Piticescu R M, Cergan R
机构信息
Anatomy Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Ophthalmology Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
出版信息
J Med Life. 2015 Jan-Mar;8(1):99-102.
INTRODUCTION
This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.
MATERIALS AND METHODS
the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus - rabbit) between August and November 2014, at "Carol Davila" University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.
RESULTS
The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.
CONCLUSIONS
The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.
引言
本研究旨在在动物模型上测试一种新型骨移植材料。该材料为纳米结构羟基磷灰石。
材料与方法
本研究于2014年8月至11月在布加勒斯特的“卡罗尔·戴维拉”医药大学依据动物模型伦理委员会规定（穴兔）进行。在使用纳米结构羟基磷灰石前后，通过下颌骨水平的CT对动物进行检测。
结果
在1个月、2个月及3个月时对动物进行CT扫描，发现下颌骨密度有所增加。3个月后，观察到骨密度与健康骨密度相当。
结论
使用该骨移植材料可能是现有材料的可行替代方案。其优势在于骨恢复后的密度与健康骨密度相似，且生产成本低，因为它由硝酸钙和磷酸二氢铵制成。
Zotero 插件