Ciuluvică R, Grădinaru S, Popescu M, Piticescu R M, Cergan R
Anatomy Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Ophthalmology Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
J Med Life. 2015 Jan-Mar;8(1):99-102.
This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.
the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus - rabbit) between August and November 2014, at "Carol Davila" University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.
The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.
The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.
本研究旨在在动物模型上测试一种新型骨移植材料。该材料为纳米结构羟基磷灰石。
本研究于2014年8月至11月在布加勒斯特的“卡罗尔·戴维拉”医药大学依据动物模型伦理委员会规定（穴兔）进行。在使用纳米结构羟基磷灰石前后，通过下颌骨水平的CT对动物进行检测。
在1个月、2个月及3个月时对动物进行CT扫描，发现下颌骨密度有所增加。3个月后，观察到骨密度与健康骨密度相当。
使用该骨移植材料可能是现有材料的可行替代方案。其优势在于骨恢复后的密度与健康骨密度相似，且生产成本低，因为它由硝酸钙和磷酸二氢铵制成。
