Pu Shenghong, Nakagome Kazuyuki, Yamada Takeshi, Matsumura Hiroshi, Yokoyama Katsutoshi, Kaneko Koichi, Kurosawa Yoichi
Division of Neuropsychiatry, Department of Brain and Neuroscience, Tottori University Faculty of Medicine, Yonago, Tottori, Japan.
Department of Psychiatry, National Center of Neurology and Psychiatry Hospital, Tokyo, Japan.
PLoS One. 2015 Apr 28;10(4):e0123972. doi: 10.1371/journal.pone.0123972. eCollection 2014.
The purpose of this study was to examine the relationship between fish consumption and prefrontal function during a cognitive task in male Japanese workers. The study included 208 male workers who underwent medical health examinations 3 months after a change in their work assignment. We measured the hemoglobin concentration changes in the prefrontal region during working memory tasks using 52-channel near-infrared spectroscopy. The frequency of fish consumption was calculated on the basis of the subjects' self-reported customary intake frequency over the previous 3 months. A significant positive relationship was observed between fish consumption and left dorsolateral prefrontal function during a working memory task. To our knowledge, this is the first study to report an association between fish consumption and functional cortical activity with an ample sample size, suggesting that fish consumption modulates functional activity in the left dorsolateral prefrontal cortex.
本研究旨在探讨日本男性工人在认知任务期间鱼类消费与前额叶功能之间的关系。该研究纳入了208名男性工人，他们在工作任务变更3个月后接受了医学健康检查。我们使用52通道近红外光谱法测量了工作记忆任务期间前额叶区域的血红蛋白浓度变化。鱼类消费频率是根据受试者自我报告的前3个月习惯性摄入频率计算得出的。在工作记忆任务期间，观察到鱼类消费与左侧背外侧前额叶功能之间存在显著的正相关关系。据我们所知，这是第一项以充足样本量报告鱼类消费与皮质功能活动之间关联的研究，表明鱼类消费可调节左侧背外侧前额叶皮质的功能活动。
