Aldemir M, Akdemir F, Okulu E, Ener K, Ozayar A, Gudeloglu A
Department of Urology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.
Department of Urology, Memorial Ankara Hospital, Ankara, Turkey.
Andrologia. 2016 Mar;48(2):189-92. doi: 10.1111/and.12430. Epub 2015 Apr 29.
We evaluated and compared blood total platelet count, mean platelet volume (MPV) and platelet distribution width (PDW) values of patients with erectile dysfunction (ED) and control subjects. A total 57 male patients (mean age 49.7 ± 12 years) with ED and 59 control men (mean age 49.7 ± 10.7 years) were included in the study. All patients were evaluated using medical history with International Index of Erectile Function (IIEF) scores, physical examination and routine blood analysis. Total blood count, including white blood cell (WBC), total platelet counts, MPV and PDW parameters, were recorded in both groups. MPV values were detected to be significantly higher in patients with ED than control group: 10.7 ± 1 and 9.72 ± 1.5, respectively (P = 0.001). Similarly, PDW values were significantly higher in patients with ED than control group: 14.6 ± 2.8 and 12.9 ± 1.9, respectively (P = 0.001). However, mean platelet and mean WBC counts were similar in both groups (P = 0.45). We demonstrated that MPV and PDW values significantly increased in patients with ED compared with the control group. According to these findings, platelet function might play an important role in patients with ED that warrants further research.
我们评估并比较了勃起功能障碍（ED）患者和对照组受试者的血液总血小板计数、平均血小板体积（MPV）和血小板分布宽度（PDW）值。该研究纳入了57例患有ED的男性患者（平均年龄49.7±12岁）和59例对照男性（平均年龄49.7±10.7岁）。所有患者均通过病史、国际勃起功能指数（IIEF）评分、体格检查和常规血液分析进行评估。两组均记录了包括白细胞（WBC）、总血小板计数、MPV和PDW参数在内的全血细胞计数。检测发现ED患者的MPV值显著高于对照组：分别为10.7±1和9.72±1.5（P = 0.001）。同样，ED患者的PDW值也显著高于对照组：分别为14.6±2.8和12.9±1.9（P = 0.001）。然而，两组的平均血小板计数和平均白细胞计数相似（P = 0.45）。我们证明，与对照组相比，ED患者的MPV和PDW值显著升高。根据这些发现，血小板功能可能在ED患者中起重要作用，值得进一步研究。
