Bayraktar Zeki, Albayrak Selami
Istanbul Medipol University, School of Medicine, Department of Urology, Istanbul.
Arch Ital Urol Androl. 2017 Mar 31;89(1):51-54. doi: 10.4081/aiua.2017.1.51.
The aim of this study was to investigate the platelet activity in patients with vasculogenic erectile dysfunction (ED).
The total blood count, including hemoglobin (Hgb), white blood cell (WBC), red blood cell (RBC), platelet (PLT) and mean platelet volume (MPV) parameters were measured in the patient (n = 70) and control groups (n = 50).
The average age was 48.1 ± 11.7 and 47.6 ± 12.3 in the patient and control groups (p = 0.8217), respectively. MPV was higher in the patient group and there was a statistically significant difference between two groups (11.27 ± 0.56 and 9.8 ± 0.91, p < 0.0001). PLT counts were lower in the patient group but there was not a statistically significant difference (196.23 ± 37.01 and 209.07 ± 36.71, p = 0.0626). In terms of haemoglobin, WBC and RBC values, there was no difference in the patient and control groups.
Finding high MPV, which reflects the platelet activity, in the patient group shows that platelets also have a role in the VED etiopathogenesis. In the case of the confirmation of this result with additional studies, the efficiency of anti-platelet therapy in the vasculogenic ED should also be researched.
本研究旨在调查血管性勃起功能障碍（ED）患者的血小板活性。
对患者组（n = 70）和对照组（n = 50）进行全血细胞计数，包括血红蛋白（Hgb）、白细胞（WBC）、红细胞（RBC）、血小板（PLT）和平均血小板体积（MPV）参数的测量。
患者组和对照组的平均年龄分别为48.1±11.7岁和47.6±12.3岁（p = 0.8217）。患者组的MPV较高，两组之间存在统计学显著差异（分别为11.27±0.56和9.8±0.91，p < 0.0001）。患者组的PLT计数较低，但无统计学显著差异（分别为196.23±37.01和209.07±36.71，p = 0.0626）。在血红蛋白、白细胞和红细胞值方面，患者组和对照组无差异。
在患者组中发现反映血小板活性的高MPV表明血小板在血管性勃起功能障碍的病因发病机制中也起作用。如果通过进一步研究证实这一结果，还应研究抗血小板治疗在血管性ED中的疗效。
