Strugala Paulina, Dudra Anna, Kucharska Alicja Z, Sokól-Lętowska Anna, Wojnicz Dorota, Cisowska Agnieszka, Walkowski Stefan, Sroka Zbigniew, Gabrielska Janina, Hendrich Andrzej B
Nat Prod Commun. 2015 Mar;10(3):467-74.
In this study we focused on the chemical composition, antioxidant, anti-inflammatory and antibacterial properties of methanol and water extracts of fruits of six species grown in south-west Poland: blackberry, blackcurrant, chokeberry, cherry, gooseberry and raspberry. No general correlation could be drawn between extract chemical properties (i.e. antioxidant and free radical scavenging) and observed biological effects. However, blackcurrant and blackberry extracts (both methanol and water) appeared to be good antioxidants and free radical scavengers, as well as effective inhibitors of E. coli adhesion to the uroepithelial cells. On the other hand, the poorest antioxidants and free radical scavengers, cherry and gooseberry extracts, also poorly affected bacterial growth, swimming ability and adhesion to epithelial cells. Surprisingly, gooseberry extracts, which showed generally weak effects, appearedto be the most effective inhibitor of bacterial biofilm formation. Additionally, most of the studied extracts showed reasonably strong anti-inflammatory properties.
在本研究中,我们聚焦于波兰西南部种植的六种水果(黑莓、黑加仑、醋栗、樱桃、醋栗和覆盆子)果实的甲醇提取物和水提取物的化学成分、抗氧化、抗炎和抗菌特性。提取物的化学性质(即抗氧化和自由基清除能力)与观察到的生物学效应之间没有普遍的相关性。然而,黑加仑和黑莓提取物(甲醇提取物和水提取物)似乎是良好的抗氧化剂和自由基清除剂,也是大肠杆菌黏附于尿道上皮细胞的有效抑制剂。另一方面,抗氧化和自由基清除能力最差的樱桃和醋栗提取物,对细菌生长、游动能力和黏附于上皮细胞的影响也很小。令人惊讶的是,通常显示出较弱作用的醋栗提取物似乎是细菌生物膜形成的最有效抑制剂。此外,大多数研究提取物显示出相当强的抗炎特性。