科威特呼吸道感染中人类博卡病毒、人类冠状病毒NL63、人偏肺病毒、人类多瘤病毒KI和WU的流行情况。
The Prevalence of Human Bocavirus, Human Coronavirus-NL63, Human Metapneumovirus, Human Polyomavirus KI and WU in Respiratory Tract Infections in Kuwait.
作者信息
Essa Sahar, Owayed Abdullah, Altawalah Haya, Khadadah Mousa, Behbehani Nasser, Al-Nakib Widad
机构信息
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.
出版信息
Med Princ Pract. 2015;24(4):382-7. doi: 10.1159/000381422. Epub 2015 Apr 24.
OBJECTIVE
The aim of this study was to investigate the prevalence of human coronavirus (HCoV)-NL63, human metapneumovirus (hMPV), human bocavirus (Boca), human polyomavirus KI (KIV) and human polyomavirus WU (WUV) in respiratory tract infections (RTI) in Kuwait.
MATERIALS AND METHODS
Respiratory samples from 735 hospitalized patients with RTI from September 2010 to April 2013 were evaluated for the presence of HCoV-NL63, hMPV, Boca, KIV and WUV using molecular assays, polymerase chain reaction (PCR) and reverse-transcription PCR.
RESULTS
Of the 735 patients, 285 (38.8%) were diagnosed with viral RTI. The distribution of respiratory viruses was hMPV: 15 (5.3%), Boca: 14 (4.9%), WUV: 10 (3.5%) and KIV: 4 (1.4%). HCoV-NL63 was not detected in any of the samples.
CONCLUSIONS
These newly discovered viruses were associated with the development of RTI in Kuwait. The rapid identification of these viral infections could aid in the control of nosocomial transmission, reduce the use of antibiotics and improve treatment and management strategies.
目的
本研究旨在调查科威特呼吸道感染（RTI）患者中人类冠状病毒（HCoV）-NL63、人偏肺病毒（hMPV）、人博卡病毒（Boca）、人类多瘤病毒KI（KIV）和人类多瘤病毒WU（WUV）的流行情况。
材料与方法
对2010年9月至2013年4月期间735例因RTI住院患者的呼吸道样本，采用分子检测、聚合酶链反应（PCR）和逆转录PCR法评估HCoV-NL63、hMPV、Boca、KIV和WUV的存在情况。
结果
735例患者中，285例（38.8%）被诊断为病毒性RTI。呼吸道病毒的分布情况为：hMPV：15例（5.3%），Boca：14例（4.9%），WUV：10例（3.5%），KIV：4例（1.4%）。所有样本均未检测到HCoV-NL63。
结论
这些新发现的病毒与科威特RTI的发生有关。快速识别这些病毒感染有助于控制医院内传播，减少抗生素的使用，并改善治疗和管理策略。
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